A Pilot Trial Examining the Merits of Combining Amantadine and Repetitive Transcranial Magnetic Stimulation as an Intervention for Persons With Disordered Consciousness After TBI.

Objective: Report pilot findings of neurobehavioral gains and network changes observed in persons with disordered consciousness (DoC) who received repetitive transcranial magnetic stimulation (rTMS) or amantadine (AMA), and then rTMS+AMA.

Participants: Four persons with DoC 1 to 15 years after traumatic brain injury (TBI).

Design: Alternate treatment-order, within-subject, baseline-controlled trial.

Neuromuscular Complications of Statin Therapy.

Purpose Of Review: This review provides an overview of neuromuscular side effects associated with statin use, their diagnosis, and treatment.

Recent Findings: The discovery of anti-HMGCR antibodies led to a better understanding of clinical aspects of statin-associated anti-HMGCR myopathy and its treatment. Statins are widely prescribed medications with well-established benefits in the treatment of cardiovascular diseases and stroke.

Recurrence Quantification Analysis of F-Waves and the Evaluation of Neuropathies.

Electrodiagnostic (EDX) patterns of neuropathic dysfunction have been based on axonal/demyelinating criteria requiring prior assumptions. This has not produced classifications of desired sensitivity or specificity. Furthermore, standard nerve conduction studies have limited reproducibility.

Prevalence and treatment of headaches in veterans with mild traumatic brain injury.

Objectives: To report the prevalence and characteristics of headaches in veterans with mild traumatic brain injury (TBI) and to describe most common treatment strategies after neurological evaluation.

Methods: We conducted a retrospective cohort study. The setting was a United States Veterans Healthcare Administration Polytrauma Network Site.

Long-term electro-clinical changes in the Lennox-Gastaut syndrome before, during, and after the slow spike-wave pattern.

Patients (64) with the Lennox-Gastaut Syndrome (LGS) were followed with EEGs (602) and clinical findings over a 42 yr period, up to 51 yrs of age. Before the slow spike-wave (SSW) complex appeared, in over one half of the patients focal discharges were seen and most often (71%) many discharges were noted, all associated with generalized seizures. With the SSW, two thirds of the patients showed additional focal discharges, again most often (72%) very many or many were noted.