Liver transplantation after radioembolization in a patient with unresectable HCC.

Background: A 58-year-old white man who was being followed by his hepatologist for nonalcoholic steatohepatitis-related liver cirrhosis and portal hypertension and who had been found to have a biopsy-proven hepatocellular carcinoma (HCC) on routine screening, self-referred to our center for a second opinion on the management of his HCC.

Investigations: Laboratory investigations, CT scan of the abdomen and chest, bone scan and technetium macroaggregated albumin scan.

Diagnosis: The patient had unresectable HCC.

Nonalcoholic fatty liver disease and cardiovascular risk.

Nonalcoholic fatty liver disease (NAFLD) is a very common cause of chronic liver disease in the United States. A large proportion of patients with NAFLD have coexisting metabolic syndrome, a major risk factor for cardiovascular disease. A strong association between NAFLD and cardiovascular disease has been long suspected, and recent studies have confirmed that cardiovascular disease is the single most important cause of mortality in this patient population.

EUS-guided FNA of proximal biliary strictures after negative ERCP brush cytology results.

Background: Accurate nonoperative diagnosis of proximal biliary strictures (PBSs) is often difficult.

Objective: To report our experience with EUS-guided FNA (EUS-FNA) of PBSs following negative or unsuccessful results with brush cytology during ERCP.

Design: Retrospective cohort study.