Pyrogallol-based dipodal optical probe as new smart analytical tool for sustainable detection of cobalt in biosystem.

The present research focuses on the micro-level detection of cobalt ions in biological and environmental samples using a new probe. The probe is a multifunctional symmetrical dipodal molecule with two pyrogallol binding units attached to the malonate scaffold through a propylene spacer. It was synthesized and characterized by H NMR, C NMR, IR, electronic spectroscopy, and mass spectrometry.

Photophysical Studies of a Catechol Based Polyfunctional Dipodal Chelator: Application for Optical Probe for Selective Detection of Fe(III).

A novel catechol based dipodal fluorescent chelator N,N'-bis[3-[(E)-(2,3-dihydroxyphenyl)methyleneamino]propyl]propanediamide(MPC), has been developed and its photophysical behaviour was studied by experimental (UV-VIS and fluorescence) and DFT method. The design of the molecule has been inspired from the naturally occurring siderophore enterobactin, a catechol based chelator with amide linkage, that shows an excellent binding efficiency towards Fe(III). The dipodal molecule (MPC) presented here, carries two catechol pendant binding moieties linked to the malonate central unit through propylene spacers by amide linkage.