Publications by authors named "Vijay A R Palkonda"
Purpose: To describe the clinical presentation and treatment outcomes of patients undergoing Ruthenium-106 (Ru) plaque brachytherapy as salvage treatment for retinoblastoma (RB) following intravenous chemotherapy (IVC).
Methods: Retrospective chart review of 44 eyes of 42 patients. The indications for plaque brachytherapy included solid tumor recurrence (n=20; 45%), solid tumor residual (n=16; 36%), new subretinal seeds (n=5; 12%), and new solid tumor (n=3; 7%).
Purpose: To describe the clinical presentation, management, and outcomes of orbital and adnexal rhabdomyosarcoma (RMS) in an Asian-Indian cohort and analyze the factors predictive of outcomes.
Methods: Retrospective interventional case series of 54 patients of histopathology-proven RMS.
Results: The mean age of presentation with RMS was 10 years (median, 7 years; range, <1-54 years).
Article Synopsis
- This study looked at how well a type of chemotherapy called platinum-based neoadjuvant chemotherapy (NACT) works for a particular kind of eyelid cancer called sebaceous gland carcinoma (eSGC).
- They treated 25 patients, and after the chemotherapy, many showed a significant reduction in tumor size, with 69% having complete control of the tumor after follow-up.
- The results suggest that NACT is a good treatment option for advanced eSGC, with serious side effects being pretty rare.
Introduction: The aim of this study was to describe the clinical features and treatment outcomes of primary subretinal seeding (SRS) in patients with intraocular retinoblastoma (RB).
Methods: Descriptive analysis of primary SRS in 47 patients (50 eyes) with RB was performed.
Results: Mean age was 19 months (range, 2-72 months), and 55% ( = 26) of the subjects were male.
Purpose: To determine the efficacy of secondary salvage intravenous chemotherapy (IVC) for refractory/recurrent retinoblastoma.
Methods: Retrospective, nonrandomized interventional case series of 41 eyes of 33 patients with recurrent retinoblastoma.
Results: Of the 33 patients, mean age at the time of commencement of salvage IVC was 5 years (median, 5 years; range, 2-8 years).
Purpose: To study the clinical presentation, treatment, and outcomes of eyes presenting with retinoblastoma and total retinal detachment.
Methods: A retrospective study of 50 eyes in 43 patients.
Results: The mean age at presentation was 15 months (median, 9 months).
Background: In India, where the annual incidence of cancer is projected to reach 1.7 million by 2020, the need for clinical research to establish the most effective, resource-guided, and evidence-based care is paramount. In this study, we sought to better understand the research training needs of radiation oncologists in India.
View Article and Find Full Text PDFPurpose: To assess the incidence, types, and outcomes of second primary tumors (SPT) in cases of retinoblastoma (RB) from a referral Tertiary eye care center METHODS: Retrospective chart review of 7 cases RESULTS: All 7 (100%) cases had bilateral RB at presentation. The mean age at diagnosis of RB was 16 months (median 7 months; range 5-72 months). Treatment of RB with intravenous chemotherapy was noted in 3 (43%) patients, 1 (14%) patient had received external beam radiotherapy (EBRT) to the orbit, 1 (14%) patient had received a combination of chemotherapy and orbital EBRT, while 4 (57%) patients had undergone primary enucleation of the worse eye and focal treatment of the better eye.
View Article and Find Full Text PDFPurpose: To compare the clinical presentation and outcomes of retinoblastoma (RB) based on age at presentation.
Methods: Retrospective comparative study of 1940 eyes of 1450 children with RB.
Results: Presentation of RB with enlarged eyeball and eyelid swelling (2% and < 1% in ≤ 1 year, 4% and 2% in > 1-2 years, 7% and 2% in > 2-3 years, and 12% and 4% in > 3 years; p < 0.
Purpose: To study the clinical presentation, treatment, and outcomes of patients with bilateral advanced intraocular retinoblastoma.
Methods: Retrospective case series of 72 patients.
Results: The mean age at presentation was 19 months.
Purpose: To study the clinical presentation and treatment outcome of patients who underwent inadvertent intraocular surgery before the diagnosis of retinoblastoma.
Design: Retrospective study of 14 patients who had undergone an inadvertent intraocular surgery before the diagnosis of retinoblastoma.
Results: The mean age at presentation to the ocular oncology clinic was 69 months.
Purpose: To study the clinical presentation, treatment, and outcome of patients with retinoblastoma (RB) in India.
Methods: Retrospective study of 1,457 patients with RB (2,074 eyes).
Results: The mean age at presentation of RB was 29 months (median, 24 months; range, <1-370 months).
Clinical Presentation and Outcomes of Stage III or Stage IV Retinoblastoma in 80 Asian Indian Patients.
J Pediatr Ophthalmol Strabismus
May 2017
Purpose: To describe the clinical features and outcomes of patients with stage III or IV retinoblastoma.
Methods: This was a retrospective study of 80 patients.
Results: Based on the International Retinoblastoma Staging System (IRSS), the tumors (n = 81) belonged to stage IIIa (n = 38, 47%), IIIb (n = 1, 1%), IVa2 (n = 10, 12%), IVb1 (n = 14, 17%), and IVb3 (n = 18, 22%).