Publications by authors named "Vignon H"

This work was carried out over a year on all the wounded patients picked up by the S.A.M.

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The investigators performed an epidaemiological study of 260 patients in intensive care and identified the causal organisms by the obtaining of various specimens: tracheobronchial, urinary, blood cultures and catheter samples. By means of these specimens, they attempted to effectuate counts for each patient and the compare each month the patients definitely infected with the infections presented by the new patients. This study attempts to demonstrate the frequency of infections of the same kind when the intensive care unit consists of a single ward without separation of the patients and where the hospital staff treat all the patients in the unit in turn.

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This study concerns 3 cases of malignant syndrome due to neuroleptics. Our aim is to clarify the nature of this syndrome and to attempt to delimit it from malignant hyperthermia. The etiology suggests that its occurence should increase with the growing use of very active neuroleptics.

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The aim of this study was to determine whether the prior injection of betamethasone was capable of preventing blood pressure changes and the fall in arterial pO2 when following the fixation of total hip protheses with methyl metacrylate. It involved 54 patients in whom systolic, diastolic and mean blood pressure (BP), arterial pO2, pCO2 and heart rate were noted at different times: T1, 15 minutes after the beginning of the operation; T2 and T3, one minute and five minutes after application of the cement; T4, at the end of the operation. There was no significant difference between the various measurements at times T1, T2, and T3 as far as blood pressure and heart rate were concerned.

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The author reports an inquiry concerning 66 patients who all had an anaphylactoid reaction. The hour of onset, the type of reaction, (skin, bronchial or systemic), their association, the drugs responsible, and the diagnostic difficulties are reviewed. In this respect, in relation to the results of the above inquiry and the data in the literature, the skin and bronchial reactions are described, and the signs of anaphylactic shock recalled.

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[Bronchial spasm and bronchial motoricity].

Ann Anesthesiol Fr

February 1978

The author recalls the phenomena which control bronchomotility, without a personal study but based on recent bibliography. After recalling the bronchial nerve supply, the chemical intermediates, the various responses of the bronchial tree to autacoids, the author recalls the association of anesthesia and bronchospasm. Although the bronchial reactions of histaminic origin are the most frequent, mechanical or chemical irritation is recalled with an elementary description of "irritant receptors" and stretch receptors.

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The well known effects of the lowering of the intraerythrocyte 2, 3, diphosphoglycerate (2, 3, DPG) level and hypothermia, on the affinity of oxygen for hemoglobin, lead the authors to study the influence of these parameters on this affinity during general anesthesia. The following observations were made in 15 adult subjects, undergoing prolonged general anaesthesia (average time: 3 hrs. 10 minutes): the dissociation curve of oxyhemoglobin (DCO) by the method of mixing, the intraerythrocyte 2,3, DPG level, the hemoglobin concentration and arterial blood parameters (PO2, PCO2, pH).

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The nitrogen balance of two groups of patients, A and B, was studied during the first four post-operative days. Groups A (31) received a daily intake of one liter of Totamine concentrée glucidique with glucose 10 p. 100 1,5 liter.

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The article analyses the results of a test conducted in 7 departments of Anaesthesia and Reanimation, concerning accidents of a histaminic type which occured following the administration of anaesthetic agents. It seems that very few of the products used lack the property of releasing histamine. The accidents observed may have more complex origins, such as the release of serotonin or bradykinin, etc.

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After enquiry in seven French anaesthetic departments, 66 cases of anaphylactic accidents during and after anaesthesia were grouped together. The following are successively described, the clinical symptomatology, the products incriminated, the treatment and course. The immuno-allergological tests were not always carried out.

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A glucid-lipid and protein compound nutriment: Trive 1000 was administered to 53 patients during the first three postoperative days in varying doses: -1.000 ml per day to a first group -1.500 ml per day to a second group.

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