Evaluating the relationship between contouring variability and modelled treatment outcome for prostate bed radiotherapy.

Contouring similarity metrics are often used in studies of inter-observer variation and automatic segmentation but do not provide an assessment of clinical impact. This study focused on post-prostatectomy radiotherapy and aimed to (1) identify if there is a relationship between variations in commonly used contouring similarity metrics and resulting dosimetry and (2) identify the variation in clinical target volume (CTV) contouring that significantly impacts dosimetry.The study retrospectively analysed CT scans of 10 patients from the TROG 08.