A new steroidal saponin from the aerial parts of .

A new steroidal saponin, torvoside R (), was isolated along with torvoside Q () and macaoside () from dichloromethane soluble-portion of the aerial parts of . Their chemical structures were elucidated using HRESIMS, 1 D- and 2 D-NMR as well as comparison with those reported in the literature. All isolated compounds (-) exhibited cytotoxicity against SK-LU-1, HepG2, MCF-7, and T24 cancer cell lines with IC values ranging from 14.

Cytotoxic activity of steroidal glycosides from the aerial parts of collected in Thua Thien Hue, Vietnam.

A phytochemical investigation of led to the isolation of eleven steroidal glycosides, including neochlorogenin 6---D-quinovopyranoside (), (22 ,23,25)-3-6,23-trihydroxy-5-spirostane 6---D-xylopyranosyl-(1→3)--D-quinovopyranoside (), neochlorogenin 6---L-rhamnopyranosyl-(1→3)--D-quinovopyranoside (), solagenin 6---L-rhamnopyranosyl-(1→3)--D-quinovopyranoside (), paniculonin A (), paniculonin B (), 6α--[-D-xylopyranosyl-(1→3)-D-quinovopyranosyl]-(25)-5α-spirostan-3-ol (), torvoside J (), torvoside K (), torvoside L () and solagenin 6---D-quinovopyranoside (). Their chemical structures were elucidated by 1D-NMR and 2D-NMR data as well as comparison with the data reported in the literature. Moreover, all isolated compounds were evaluated for their cytotoxic activities against SK-LU-1, HepG2, MCF-7 and T24 cancer cell lines.

Cytotoxic and anti-inflammatory activities of secondary metabolites from growing in Thua Thien Hue, Vietnam.

A new ursane-type triterpene, 3,23,24-trihydroxyurs-12-en-28-oic acid (), together with eight known compounds (-) were isolated from the aerial parts of . Among them, compounds - were found for the first time from the genus , while compounds - were reported from for the first time. Their structures were elucidated by analysis of HR-ESI-MS and NMR (H-NMR, C-NMR, HSQC, and HMBC) spectra, as well as comparison with those reported in the literature.

Identification Of Potential Cytotoxic Inhibitors From .

A phytochemical investigation of led to the isolation of six withanolides, including withanolide E (), withaperuvin C (), 4-hydroxywithanolide E (), 28-hydroxywithaperuvin C (), physaperuvin G (), and 4-deoxywithaperuvin (). Their chemical structures were elucidated by 1 D-NMR and 2 D-NMR data, as well as comparison with the data reported in the literature. All isolated compounds were evaluated for their cytotoxic activity against HepG2, SK-LU-1, and MCF7 cancer cell lines.

Bioactive compounds from the aerial parts of .

is an important medicinal plant used in Vietnam to treat many diseases such as backache, burns, diarrhea, and swelling. In order to study the chemical constituents in the aerial parts of , five compounds, including two xanthones (-), and three benzophenones () were isolated from the aerial parts of the with various chromatographic separations. Their chemical structures were established on the basis of spectroscopic data such as 1D- and 2D-NMR, HR-ESI-MS.