Publications by authors named "Vien Le Minh"
In vitro activity of colistin in antimicrobial combination against carbapenem-resistant Acinetobacter baumannii isolated from patients with ventilator-associated pneumonia in Vietnam.
J Med Microbiol
October 2015
Acinetobacter baumannii has become one of the major infection threats in intensive care units (ICUs) globally. Since 2008, A. baumannii has been the leading cause of ventilator-associated pneumonia (VAP) in our ICU at an infectious disease hospital in southern Vietnam.
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- * A comprehensive genomic analysis of over 300 K. pneumoniae isolates has led to the identification of three distinct species and revealed over 150 lineages within K. pneumoniae (KpI) that are linked to human infections.
- * The study highlights a large accessory genome with numerous virulence genes associated with invasive disease, raising concerns about the potential emergence of untreatable K. pneumoniae infections due to the integration of resistance and virulence traits.
Studying the antimicrobial drug resistance of nasopharyngeal or nasal carriage isolates of Streptococcus pneumoniae in children is likely to have predictive potential for invasive isolates. Streptococcus pneumoniae nasal carriage was studied in 1422 Vietnamese children. Forty-six percent of 536 isolates showed reduced susceptibility to penicillin and 7% showed intermediate susceptibility to ceftriaxone; and 50% of 518 isolates showed resistance to erythromycin.
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