Publications by authors named "Vidya Devanatha Desikan Sheshadri"
Vascular Endothelial Growth Factor Single Nucleotide Polymorphism +405 G/C (rs2010963) is associated with Levels, Infection Severity, and Amputation among South Indian Diabetic Foot Ulcer Patients.
Priyanka Ganapathy Vidya Devanatha Desikan Sheshadri Rajesh Sarkar Sumathi Jones Krishnamoorthy Gunasekaran
Evid Based Complement Alternat Med
April 2023
Article Synopsis
- - The study investigates the relationship between genetic factors regulating vascular endothelial growth factor (VEGF) and diabetic foot ulcers (DFU) in individuals with type 2 diabetes mellitus (T2DM).
- - It involved 754 participants, including healthy controls, T2DM subjects, and DFU patients, using techniques like PCR-RFLP and ELISA to analyze genetic variations and VEGF levels.
- - Findings indicate lower VEGF levels in DFU patients, particularly those with the CC genotype, which correlates to increased severity of ulcers and higher rates of major amputations.