Synthesis and in vitro antimicrobial study of 4-thiazolidinone containing sulfanilamide.

The title compounds, 3-allyl-2-sulfanylamido-4-thiazolidinones (2a-d), have been synthesized after substitution of amino group of sulfanylamide with allylisothiocyanate and cyclization into 4-thiazolidinones. The synthesized compounds were tested for their antibacterial and antifungal activity (MIC) in vitro) against microorganisms: S. aureus, E.

Study of diversity of anthocyanin composition in bilberry (Vaccinium myrtillus L.) fruits.

Qualitative and quantitative composition of anthocyanins in bilberry (Vaccinium myrtillus L.) fruits was assayed. The aim of our study was to evaluate total anthocyanin content and their composition in bilberries collected from various regions and at different time.

[Determination of benzodiazepine derivatives mixture by high performance liquid chromatography].

By increasing tendency of intoxication with several preparations at a time, there is lack of data in the sources of information about the chemical-toxicological research of the psychotropic drugs in the mixture. The aim of this research was to determine possibility of qualitative analysis of benzodiazepines derivatives--diazepam, flunitrazepam, nitrazepam, oxazepam and tetrazepam in the mixture, extracted from biological fluid (blood). The high performance liquid chromatography was used for the investigation, the reagents--tablets of diazepam, flunitrazepam, nitrazepam, oxazepam and tetrazepam.

[Analysis of benzodiazepine derivative mixture by gas-liquid chromatography].

The analysis of mixture of benzodiazepine derivates (chlordiazepoxide, flunitrazepam, medazepam, nitrazepam, oxazepam and tetrazepam) by gas--liquid chromatography (GLC) in purpose to separate and identify these psychotropic drugs in mixture is presented in this article. The experiment was carried out in vitro, accommodating this method for identification and separation of drugs, isolated from biological objects (blood and urine). Referring to data of annual reports of chemical investigations (1) above-mentioned psychotropic drugs are very frequent among drug intoxication.

[Poisonings with psychotropic drug mixtures: analysis using the thin-layer chromatography method].

It is observed increase in number of remedy intoxications in Lithuania, especially important is intoxication with psychotropic drugs and their mixtures. The thin-layer chromatography (TLC) method was proposed for separation and identification of drugs in mixture aminazine: nitrazepam: barbamylum. The mixture of these drugs excreted from body fluids (blood and urine) was investigated by TLC.