A review of implementation frameworks to operationalize health technology assessment recommendations for medical technologies in the Singapore setting.

Background: Methodologies of health technology assessment (HTA) for medical technologies are well established; yet, operational frameworks that enable appropriate uptake of HTA recommendations into routine clinical practice are lacking. This review aims to identify the key themes needed to guide the planning and implementation of HTA subsidy decisions for medical technologies such as diagnostics, medical devices, and services and to monitor their impact on a complex multipayer healthcare system like Singapore.

Methods: A literature search of implementation frameworks was conducted up to 20 December 2020 and was documented in a flow diagram.