Stimulation of Dopamine D4 Receptors in the Nucleus Accumbens Shell Increases Palatable Food Intake in Satiated Male Rats: Modulation by NMDA and AMPA Receptors.

Background/objectives: Palatability significantly influences food consumption, often leading to overeating and obesity by activating the brain's reward systems. The nucleus accumbens (NAc) plays a central role in this process, modulating reward mechanisms primarily via dopamine through D2-like receptors (D2R, D3R, D4R). While the involvement of D2 receptors in feeding is well-documented, the role of D4 receptors (D4Rs) is less clear.

Ecoepidemiology of Chagas Disease in a Biological Corridor in Southeastern Mexico: A Promising Approach to Understand the Risk of Chagas Disease.

Ecoepidemiology is an emerging field that attempts to explain how biotic, environmental, and even social factors influence the dynamics of infectious diseases. Particularly in vector-borne diseases, the study under this approach offers us an overview of the pathogens, vectors, and hosts that coexist in a given region and their ecological determinants. As a result of this, risk predictions can be established in a changing environment and how it may impact human populations.

Chagas' disease among school students from Chiapas, Mexico: Two cases of Chagasic cardiomyopathy.

Background & Objectives: Chagas disease is a vector-borne life-threatening illness originally confined to the Americas. Seroprevalence studies have been reported in the Mexican state of Chiapas; nevertheless, no clinical/cardiological studies have been conducted to detect underage cases. The aim of the present work was to detect underage cases in the Mexican state of Chiapas.

A Trypanosoma cruzi strain from southern Mexico is more virulent for male mice in part by blocking the immune response.

Introduction: Chagas disease is a neglected disease in the American continent. The southern Mexican state of Chiapas has the highest incidence rate of Chagas disease in the country. The disease, mainly caused by Tripanosoma cruzi in Mexico, is more prevalent in males than in females but the scientific basis for the sex-related tropism is not completely understood.