Publications by authors named "Victoria Shi"

The strength of a systematic review hinges in large part on the quality of evidence it appraises. Observational studies, including cohort studies and case series, are positioned lower on the hierarchy of evidence, with cohort studies typically higher than case series. The often subtle differences between these study designs may lead to misclassification and can impact the strength of recommendations derived from such data.

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Background: Fragility Index (FI) is increasingly used to assess robustness of statistically significant p-values reported in randomized controlled trials (RCTs). FI represents the lowest number of non-events changed to events that would make study findings non-significant. This methodological survey was designed to assess the fragility of the evidence for extended VTEp following major abdominopelvic surgery.

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  • The FDA regulates medical devices to make sure they are safe and work well before they can be sold.
  • A survey was done to understand how the FDA's Medical Devices Advisory Committee makes decisions and what could be improved.
  • Out of 92 panel members, most were men and white, and many thought the information from the FDA was fair and that important trials were often designed well.
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  • A study was conducted to analyze how often dermatologic surgeons face challenges in identifying the locations of skin cancer tumors before surgery.
  • Out of over 17,000 cases, only 0.60% involved uncertain sites, with these cases more common in older, male patients who had biopsies done over a month prior.
  • Surgeons commonly used various methods to confirm tumor locations, achieving success in identifying 82% of these uncertain sites, while some surgeries were delayed, especially for non-facial tumors.
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Generative-AI (GAI) models like ChatGPT are becoming widely discussed and utilized tools in medical education. For example, it can be used to assist with studying for exams, shown capable of passing the USMLE board exams. However, there have been concerns expressed regarding its fair and ethical use.

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  • Diffuse dermal angiomatosis (DDA) is a rare, benign skin condition that mainly affects middle-aged women, particularly on the breasts.
  • The case discussed involves a 56-year-old woman with bilateral DDA linked to risk factors like smoking that cause tissue hypoxia.
  • Addressing the hypoxic factors led to the healing of the ulcers associated with DDA, suggesting that managing these risks can improve the condition.
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Background: Some observational data have suggested that anastomotic leak may be reduced with triple-row staple technology compared to double-row staple technology. We aimed to investigate this further by performing a systematic review comparing double- and triple-row staple technology for colorectal anastomoses.

Methods: This systematic review was reported in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines.

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  • Acne scarring, resulting from inflammation common in many individuals, negatively affects self-esteem and social acceptance, prompting a search for effective treatments.
  • A study evaluated the effectiveness of multiple subcision treatments on rolling acne scars, enrolling five patients who received treatment on one side of their face while the other side served as a control.
  • Results showed that the treated side had significantly greater improvements in scar appearance and patient satisfaction compared to the untreated side, indicating that subcision may effectively enhance the appearance of rolling acne scars.
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Therapeutic options for acne scars include subcision and suction with microdermabrasion, but these treatment modalities have not been studied in conjunction. To compare effectiveness of subcision alone versus subcision with suction for the treatment of facial acne scars. Randomized, split-faced, evaluator-blinded control trial.

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Background: People living with HIV (PLWH) with multidrug-resistant (MDR) viruses have limited therapeutic options and present challenges regarding clinical management. Recent studies have shown that passive transfer of combination broadly neutralizing antibodies (bNAbs) against HIV and anti-domain 1 CD4 antibody UB-421 can sustain virologic suppression in PLWH in the absence of antiretroviral therapy (ART). Yet studies addressing the therapeutic potential of these antibodies and/or detailed characterization of immunologic and virologic parameters in PLWH with MDR HIV are lacking.

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  • Early detection of cervical cancer recurrence is crucial for improving patient outcomes, with serum squamous cell carcinoma antigen (SCCA) serving as a potential biomarker.
  • In a study of 227 patients, those with elevated follow-up SCCA levels showed a higher likelihood of recurrence, with the follow-up SCCA demonstrating high specificity and negative predictive value.
  • However, for patients with normal pre-treatment SCCA levels, the test's utility was limited, indicating a need for better methods of surveillance in this group.
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  • Inconsistent reporting of outcomes in rosacea clinical trials is hindering accurate data analysis and meta-analyses, highlighting the need for standardized outcome measures.
  • A core outcome set (COS) was developed through systematic literature reviews and a Delphi process, involving feedback from physicians and patients to identify essential outcomes in rosacea trials.
  • The final COS includes 8 key domains, such as skin symptoms and patient satisfaction, which aim to enhance the comparability and relevance of future rosacea research and interventions.
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