Resting metabolic rate in relation to incident disability and mobility decline among older adults: the modifying role of frailty.

Background: Alterations in resting metabolic rate (RMR), the largest component of daily total energy expenditure, with aging have been shown in various studies. However, little is known about the associations between RMR and health outcomes in later life.

Aims: To analyze whether RMR is associated with incident disability and mobility decline in a 10-year longitudinal study, as well as the moderating role of frailty in these associations.

Limits of stability and falls during a multicomponent exercise program in faller older adults: A retrospective cohort study.

Background/objetives: Multicomponent exercise programs have been demonstrated to prevent falls in older adults. However, the underlying responsible mechanisms are not clear. We aimed to analyze the association between changes in the limits of stability (LOS) as a relevant balance component, and falls occurrence during a multicomponent physical exercise program.

Frailty, depression risk and 10-year hospitalization in older adults. The FRADEA study.

Objectives: To determine whether the interaction between frailty status and depression risk is associated with hospitalization density in older adults.

Methods: Ongoing cohort study in 794 subjects aged over 70 years from Albacete (Spain). Data were collected on depression risk, frailty, hospitalizations, and covariates.

Psychological and Functional Impact of COVID-19 in Long-Term Care Facilities: The COVID-A Study.

Objective: To analyze the psychological and functional sequelae of the COVID-19 pandemic among older adults living in long term care facilities (LTCFs).

Design: Cohort longitudinal study SETTING ANT PARTICIPANTS: A total of 215 residents ≥ 65 years without moderate-to-severe cognitive impairment, living in five LTCFs in Albacete (Spain).

Measurements: Baseline on-site data were collected between March - June 2020 and three-month follow-up between June to September 2020.

Baricitinib reduces 30-day mortality in older adults with moderate-to-severe COVID-19 pneumonia.

Background: Older adults are at the highest risk of severe disease and death due to COVID-19. Randomized data have shown that baricitinib improves outcomes in these patients, but focused stratified analyses of geriatric cohorts are lacking. Our objective was to analyze the efficacy of baricitinib in older adults with COVID-19 moderate-to-severe pneumonia.

The Functional Continuum Scale in Relation to Hospitalization Density in Older Adults: The FRADEA Study.

Background: There is a need to know the relationship between function and hospitalization risk in older adults. We aimed at investigating whether the Functional Continuum Scale (FCS), based on basic (BADL) and instrumental (IADL) activities of daily living and frailty, is associated with hospitalization density in older adults across 12 years of follow-up.

Methods: Cohort study, with a follow-up of 12 years.

COVID-19 outbreak in long-term care facilities from Spain. Many lessons to learn.

Background/objectives: To analyze mortality, costs, residents and personnel characteristics, in six long-term care facilities (LTCF) during the outbreak of COVID-19 in Spain.

Design: Epidemiological study.

Setting: Six open LTCFs in Albacete (Spain).