Publications by authors named "Victoria S Zucherato"
Article Synopsis
- The study focused on investigating other respiratory viruses in pediatric patients with acute symptoms who tested negative for SARS-CoV-2 during the Omicron wave.
- Metagenomic analysis of 96 nasopharyngeal swab samples showed that respiratory syncytial virus and enteroviruses were the most common, indicating significant health risks.
- The findings suggest that viral metagenomics should be prioritized in clinical settings for better diagnosis and public health policies aimed at protecting children's health from various viral infections.
Viral metagenomics has been extensively applied for the identification of emerging or poorly characterized viruses. In this study, we applied metagenomics for the identification of viral infections among pediatric patients with acute respiratory disease, but who tested negative for SARS-CoV-2. Twelve pools composed of eight nasopharyngeal specimens were submitted to viral metagenomics.
View Article and Find Full Text PDFArticle Synopsis
- Merkel cell polyomavirus (MCPyV) is linked to Merkel cell carcinoma and its prevalence in Brazilian blood donors was studied.
- The research analyzed 450 serum samples from donors across three regions in Brazil, finding an overall MCPyV DNA prevalence of 1.1%.
- Prevalence varied by region, with North and South Brazil at 1.33% and Central-West at 0.6%, showing generally low viral loads in positive samples, prompting the need for further studies on the virus's impact on transfusion medicine.
Human gemykibivirus-2 (HuGkV-2) belonging to the Gemykibivirus genus (Genomoviridae family) is an emerging DNA virus which has been described as a component of the virome of a wide variety of samples including clinical ones. So far, the HuGkV-2 DNA prevalence in the human population as well as its clinical impact are completely unknown. The objective of this study was to investigate the HuGkV-2 DNA prevalence among Brazilian healthy blood donors from three different geographic regions.
View Article and Find Full Text PDFViral metagenomics is widely applied to characterize emerging viral pathogens but it can also reveal the virome composition in health and disease. The evaluation of the virome in healthy blood donors can provide important knowledge on possible transfusion threats. Currently, there is still a paucity of information regarding the virome of blood donors who test positive for routinely tested blood-borne infections.
View Article and Find Full Text PDFIt has been suggested that menstrual blood-derived mesenchymal stem/stromal cells (MenMSCs) are associated with the etiopathogenesis of endometriosis and considerable effort has been invested in searching for target genes and deciphering associated molecular pathways. However, reference gene stability for proper reproducible normalization in the analyses of the expression data validation is still unexplored in this experimental context. Therefore, in this exploratory study, we used stringent case and control selection criteria and collected menstrual blood from women with a laparoscopic diagnosis of advanced endometriosis and from fertile women without endometriosis.
View Article and Find Full Text PDF