Publications by authors named "Victoria Robbins"
Background: Although it is well established that antibiotic prophylaxis is not needed in soft tissue upper extremity cases, there is still no definitive consensus when hardware implantation is involved. We hypothesize that antibiotic prophylaxis is not necessary and there is no difference in postoperative surgical site infection rates regardless of preoperative antibiotic administration.
Methods: A retrospective cohort analysis was performed on upper extremity surgical cases with hardware implantation performed at a single institution amongst 5 hand surgeons between November 2021 and November 2023.
Article Synopsis
- Hutchinson-Gilford Progeria Syndrome (HGPS) is a rare genetic disorder that causes accelerated aging and typically results in a life expectancy of around 14 years.
- The condition is primarily caused by a mutation in the LMNA gene, which leads to the production of a harmful protein called progerin, affecting DNA repair processes.
- Research indicates that progerin expression increases the occurrence of imprecise DNA end-joining during repair, moving away from the more accurate homologous recombination method, potentially contributing to the symptoms of accelerated aging in HGPS patients.