Controlled colonic insufflation by a remotely triggered capsule for improved mucosal visualization.

Background And Study Aims: Capsule endoscopy is an attractive alternative to colorectal cancer screening by conventional colonoscopy, but is currently limited by compromised mucosal visibility because of the lack of safe, controlled colonic insufflation. We have therefore developed a novel system of untethered, wireless-controlled carbon dioxide (CO2) insufflation for use in colonic capsule endoscopy, which this study aims to assess in vivo.

Material And Methods: This observational, nonsurvival, in vivo study used five Yorkshire-Landrace cross swine.