Modeling the Immune Response for Pathogenic and Nonpathogenic Infections in Human Lung Microvasculature Endothelial Cells.

Hantaviruses, genus , family , order , are negative-sense, single-stranded, tri-segmented RNA viruses that persistently infect rodents, shrews, and moles. Of these, only certain virus species harbored by rodents are pathogenic to humans. Infection begins with inhalation of virus particles into the lung and trafficking to the lung microvascular endothelial cells (LMVEC).