Publications by authors named "Victoria Murry-Tait"

Background: ERK5 is a member of the mitogen activated protein kinase family activated by certain mitogenic or stressful stimuli in cells, but whose physiological role is largely unclear.

Results: To help determine the function of ERK5 we have used gene targeting to inactivate this gene in mice. Here we report that ERK5 knockout mice die at approximately E10.

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Synopsis of recent research by authors named "Victoria Murry-Tait"

  • - Victoria Murry-Tait's research primarily focuses on the functional roles of specific genes in development, particularly genes related to the mitogen-activated protein kinase family, such as ERK5.
  • - Her study on ERK5 knockout mice revealed significant developmental defects, leading to embryonic and placental issues that resulted in lethality by embryonic day 10 (E10).
  • - The findings contribute to a better understanding of the physiological role of ERK5 and its importance in normal embryonic development, highlighting its potential implications in developmental biology and congenital disorders.