Toward Multimodal Modeling of Emotional Expressiveness.

Emotional expressiveness captures the extent to which a person tends to outwardly display their emotions through behavior. Due to the close relationship between emotional expressiveness and behavioral health, as well as the crucial role that it plays in social interaction, the ability to automatically predict emotional expressiveness stands to spur advances in science, medicine, and industry. In this paper, we explore three related research questions.

gfoRmula: An R Package for Estimating the Effects of Sustained Treatment Strategies via the Parametric g-formula.

Researchers are often interested in estimating the causal effects of sustained treatment strategies, i.e., of (hypothetical) interventions involving time-varying treatments.

Enhancing GABA Signaling during Middle Adulthood Prevents Age-Dependent GABAergic Interneuron Decline and Learning and Memory Deficits in ApoE4 Mice.

Unlabelled: Apolipoprotein E4 (apoE4) is the major genetic risk factor for Alzheimer's disease (AD). However, the underlying mechanisms are still poorly understood. We previously reported that female apoE4 knock-in (KI) mice had an age-dependent decline in hilar GABAergic interneurons that correlated with the extent of learning and memory deficits, as determined by Morris water maze (MWM), in aged mice.

Evaluation of the patient with neck versus shoulder pain.

Neck and shoulder pain are common complaints among the general population, being the second and third most common musculoskeletal complaints, respectively, after back pain in the primary care setting. Differentiating between neck and shoulder pain can be challenging, as both share symptoms and physical examination findings. The differential diagnoses of neck and shoulder pain are extensive.

Evaluation of prenatal-onset osteochondrodysplasias by ultrasonography: a retrospective and prospective analysis.

The osteochondrodysplasias or skeletal dysplasias are a heterogenous group of over 350 distinct disorders of skeletogenesis. Many manifest in the prenatal period, making them amenable to ultrasound prenatal diagnosis. A retrospective analysis evaluated 1,500 cases referred to the International Skeletal Dysplasia Registry (ISDR) to determine the relative frequency of specific osteochondrodysplasias and correlation of ultrasound versus radiographic diagnoses for these disorders.

Preischemic induction of TNF-alpha by physical exercise reduces blood-brain barrier dysfunction in stroke.

This study explores the neuroprotective action of tumor necrosis factor-alpha (TNF-alpha) induced during physical exercise, which, consequently, reduces matrix metalloproteinase-9 (MMP-9) activity and ameliorates blood-brain barrier (BBB) dysfunction in association with extracellular signal-regulated kinase 1 and 2 (ERK1/2) phosphorylation. Adult male Sprague-Dawley rats were subjected to exercise on a treadmill for 3 weeks. A 2-h middle cerebral artery occlusion and reperfusion was administered to exercised and nonexercised animals to induce stroke.