Therapeutic strategies for invasive fungal infections in neonatal and pediatric patients: an update.

Introduction: Invasive fungal infections (IFIs) in neonatal and pediatric patients are still associated with high morbidity and mortality, increased length of hospital stay and high healthcare cost. Two key components are prerequisite to combat pediatric IFIs; first, definition of the 'at-risk' populations that could benefit the most from prophylactic treatment and second, prompt initiation of effective antifungal therapy.

Areas Covered: In this article, updated prevention and targeted therapeutic approaches for IFIs in neonates and immunocompromised children are reviewed.