Publications by authors named "Victoria I Lioudyno"

Article Synopsis
  • The study analyzed homocysteine (HCy) and vitamin levels, as well as genotypes of key gene polymorphisms related to folate metabolism in children with early-stage multiple sclerosis (MS) and compared them with healthy controls and patients with long-term MS.
  • Results showed elevated HCy levels in children at MS onset without any vitamin B6, B9, or B12 deficiencies, suggesting a unique metabolic issue rather than a general vitamin deficiency.
  • The findings indicate that high HCy levels can serve as a marker for functional disorders in folate metabolism associated with pediatric MS, potentially guiding new prevention and treatment strategies.
View Article and Find Full Text PDF

Long (D2L) and short (D2S) isoform of the D2 dopamine receptor are believed to play different roles in behavioral regulation. However, little is known about differential regulation of these isoforms mRNA expression during the process of learning in physiological and pathological states. In this study, we have investigated the combined effect of training in active avoidance (AA) paradigm and chronic early life treatment with pro-inflammatory cytokine interleukin (IL)-1β (1μg/kg i.

View Article and Find Full Text PDF

Tumors spontaneously develop central necroses due to inadequate blood supply. Recent data indicate that dead cells and their products are immunogenic to the host. We hypothesized that macrophage tumor-dependent reactions can be mediated differentially by factors released from live or dead tumor cells.

View Article and Find Full Text PDF