Publications by authors named "Victoria Grillmayr"
Vitamin D and its role in the coronavirus-19 disease (COVID-19) pandemic has been controversially discussed, with inconclusive evidence about vitamin D3 (cholecalciferol) supplementation in COVID-19 patients. Vitamin D metabolites play an important role in the initiation of the immune response and can be an easily modifiable risk factor in 25-hydroxyvitamin D (25(OH)D)-deficient patients. This is a multicenter, randomized, placebo-controlled double-blind trial to compare the effect of a single high dose of vitamin D followed by treatment as usual (TAU) of daily vitamin D daily until discharge versus placebo plus TAU in hospitalized patients with COVID-19 and 25(OH)D-deficiency on length hospital stay.
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- The COVID-19 pandemic has led to many deaths and a need for new treatments, with factors like age, sex, and vitamin D deficiency linked to worse outcomes.
- Vitamin D is thought to enhance the immune response and may help lessen the severity of COVID-19 in those who are deficient, but the direct connection is unclear.
- The study aims to rigorously test whether high-dose vitamin D supplementation can improve recovery times in vitamin D-deficient COVID-19 patients compared to those receiving standard treatment.