Water sorption studies with mesoporous multivariate monoliths based on UiO-66.

Hierarchical linker thermolysis has been used to enhance the porosity of monolithic UiO-66-based metal-organic frameworks (MOFs) containing 30 wt% 2-aminoterephthalic acid (BDC-NH) linker. In this multivariate ( mixed-linker) MOF, the thermolabile BDC-NH linker decomposed at ∼350 °C, inducing mesopore formation. The nitrogen sorption of these monolithic MOFs was probed, and an increase in gas uptake of more than 200 cm g was observed after activation by heating, together with an increase in pore volume and mean pore width, indicating the creation of mesopores.

Flexible Coordination Network Exhibiting Water Vapor-Induced Reversible Switching between Closed and Open Phases.

That physisorbents can reduce the energy footprint of water vapor capture and release has attracted interest because of potential applications such as moisture harvesting, dehumidification, and heat pumps. In this context, sorbents exhibiting an S-shaped single-step water sorption isotherm are desirable, most of which are structurally rigid sorbents that undergo pore-filling at low relative humidity (RH), ideally below 30% RH. Here, we report that a new flexible one-dimensional (1D) coordination network, [Cu(HQS)(TMBP)] (HHQS = 8-hydroxyquinoline-5-sulfonic acid and TMBP = 4,4'-trimethylenedipyridine), exhibits at least five phases: two as-synthesized open phases, α ⊃ HO and β ⊃ MeOH; an activated closed phase (γ); CO (δ ⊃ CO) and CH (ϵ ⊃ CH) loaded phases.

Photo-responsive functional gold nanocapsules for inactivation of community-acquired, highly virulent, multidrug-resistant MRSA.

The indiscriminate and sporadic use of antibiotics has contributed to the emergence of drug resistance phenomenon in bacteria including but not limited to Staphylococcus aureus. These drug-resistant bacteria have been threatening safety in hospitals and adversely affecting human health. Here we report a strategy to design photo-stimulated theranostic nanoprobes against methicillin-resistant Staphylococcus aureus (MRSA) "superbug" USA300.

Reversible Switching between Nonporous and Porous Phases of a New SIFSIX Coordination Network Induced by a Flexible Linker Ligand.

Closed-to-open structural transformations in flexible coordination networks are of potential utility in gas storage and separation. Herein, we report the first example of a flexible SiF-pillared square grid material, [Cu(SiF)(L)] (L = 1,4-bis(1-imidazolyl)benzene), . exhibits reversible switching between nonporous () and several porous (, , , and ) phases triggered by exposure to N, CO, or HO.

Environmentally Friendly Enzyme Immobilization on MOF Materials.

Metal-organic framework (MOF) materials have revolutionized the applications of nanoporous materials. They can be potentially used in separation, storage, and catalysis, among other applications. Since their discovery in 1999 (Li et al.

Silica nano supra-assembly for the targeted delivery of therapeutic cargo to overcome chemoresistance in cancer.

Cancer cells become resistant over the period to chemotherapeutic drugs and pose a challenging impediment for oncologists in providing effective treatment. Nanomedicine allows to overcome chemoresistance and is the focus of our investigation. Silica nanostructures have been highlighted as an interesting drug delivery platform in vitro and in vivo applications.