Publications by authors named "Victoria E Makal"

Article Synopsis
  • * Serpentine AAV (SAAV), which does not spread in primate populations, is explored as a potential solution; the study investigates its structural properties, receptor interactions, and ability to evade specific antibodies using cryo-EM and various assays.
  • * Findings reveal that SAAV primarily binds to terminal sialic acid, similar to some other AAV types, and while it can evade certain mouse antibodies, about 25% of human sera still recognize it, indicating possible challenges for its use in gene delivery.
View Article and Find Full Text PDF