Increased alcohol consumption during the COVID-19 pandemic: A cross-sectional study.

Background: The coronavirus disease 2019 (COVID-19) pandemic has significantly impacted health, mental well-being, and societal functioning, particularly for individuals with psychiatric conditions and substance use disorders. Recent evidence highlights a concerning increase in alcohol consumption during the pandemic, with a study spanning 2015-2020 indicating heightened usage, especially among young and middle-aged adults, for relaxation and tension relief. Additionally, addressing challenges exacerbated by the pandemic, another study underscored persistent barriers to healthcare access, resulting in increased alcohol and tobacco use rates and limited healthcare options.

The Potential Role of NOD2/CARD15 Genotype as a Prognostic Indicator for Bone Marrow Transplantation Outcomes in Patients With Acute Lymphoblastic Leukemia and Acute Myeloid Leukemia: A Systematic Review.

Hematopoietic stem-cell transplantation (HSCT) has emerged as a groundbreaking therapeutic option for acute myeloid leukemia (AML) and specific subtypes of acute lymphoblastic leukemia (ALL). The prognostic significance of the NOD2/CARD15 gene has been explored alongside various factors, encompassing diverse patient cohorts and gene variants. Siblings and unrelated donors used for stem cell transplantation exhibit significant associations between their genetic variations and graft-versus-host disease incidence.

The Benefits of Integrative Medicine for Pain Management in Oncology: A Narrative Review of the Current Evidence.

The aim of this evidence-based study is to narrate and evaluate the current evidence on recommendations for practicing physicians and other healthcare providers regarding integrative approaches to managing pain in patients with cancer. This review will assess the guideline recommendations and analyze the role of integrative medicine in addressing cancer pain in patients. The literature search highlights relevant studies that will inform evidence-based recommendations for practicing physicians, highlighting their relevance and weaknesses.

Treatment of Advanced Metastatic Prostate Cancer Using Molecular-Targeted Therapy: Radioligand Lutetium-177 Prostate-Specific Membrane Antigen.

This study investigates the predicting factors of the biochemical response and survival of patients with advanced metastatic prostate cancer who underwent therapy with radioligand lutetium-177 (Lu)-prostate-specific membrane antigen (PSMA), often referred to as [Lu]Lu-PSMA. This study is a review of the previous literature. This study included articles published in the last 10 years in the English language.

Gene Therapy for Spinal Muscular Atrophy (SMA): A Review of Current Challenges and Safety Considerations for Onasemnogene Abeparvovec (Zolgensma).

Spinal Muscular Atrophy (SMA) is a genetic disease that causes weakness and wasting in the voluntary muscles of infants and children. SMA has been the leading inherited cause of infant death. More specifically, SMA is caused by the absence of the SMN1 gene.

The Impact of Early Morning Training Sessions on Total Sleep Time in Collegiate Athletes.

Early morning training sessions may affect sleep quantity in athletes. The purpose of this study is to examine differences in total sleep time of collegiate athletes on nights prior to early morning training sessions relative to non-training nights. Wristwatch monitors equipped with photoplethysmography and accelerometer technology were worn by 18 NCAA Division III collegiate athletes (Age: 20.

Seasonal Accumulated Workloads in Collegiate Women's Soccer: A Comparison of Starters and Reserves.

Research quantifying the unique workload demands of starters and reserves in training and match settings throughout a season in collegiate soccer is limited. The purpose of the current study is to compare accumulated workloads between starters and reserves in collegiate soccer. Twenty-two NCAA Division III female soccer athletes (height: 1.

Prevalence and Amounts of Common Ingredients Found in Energy Drinks and Shots.

Background: Energy drinks are one of the most popular packaged beverage products consumed within the United States (US). Energy drinks are considered a functional beverage, a category that also includes sports drinks and nutraceutical beverages.

Purpose: The focus of the current study was to examine the nutrition fact panels of the top selling commercially available energy drink and energy shot products within the US to characterize common ingredient profiles to help establish a standard definition and ingredient profile of energy drinks and energy shots for consumers, health care practitioners, and researchers.

Short-term drought triggers defence mechanisms faster than ABA accumulation in the epiphytic bromeliad Acanthostachys strobilacea.

Epiphytic bromeliads might experience drought after a few hours without water, which is especially critical during early life stages. Consequently, juvenile epiphytic bromeliads probably rely on short-term activation of drought tolerance strategies, although the biochemical processes involved are still poorly understood. In this study, we aimed to evaluate the short-term drought response of juvenile plants of the epiphytic bromeliad Acanthostachys strobilacea (Schult.

Fructan and antioxidant metabolisms in plants of Lolium perenne under drought are modulated by exogenous nitric oxide.

Drought is a major environmental factor that can trigger oxidative stress and affect plant growth and productivity. Previous studies have shown that exogenous nitric oxide (NO) can minimize oxidative stress-related damage through the modulation of antioxidant enzyme activity. Fructan accumulation also has an important role in drought tolerance, since these carbohydrates participate in osmoregulation, membrane protection and oxidant scavenging.

Antioxidant capacity along the leaf blade of the C-CAM facultative bromeliad Guzmania monostachia under water deficit conditions.

Guzmania monostachia (L.) Rusby ex Mez is an epiphytic, rosette-shaped bromeliad that displays variable degrees of crassulacean acid metabolism (CAM) along the leaf under water deficit. The aim of our study was to evaluate whether the production-scavenging system of reactive oxygen species (ROS) along the leaf length of G.

Rapid responses of plants to temperature changes.

Temperature is one of the main environmental factors that affect plant metabolism. Considering that plants are sessile, their survival depends on the efficient activation of resistance responses to thermal stress. In this comprehensive review, we discuss recent work on rapid biochemical and physiological adjustments, herein referred to as those occurring during the first few hours or a few days after the beginning of the change in the ambient temperature.

Adjustments in CAM and enzymatic scavenging of HO in juvenile plants of the epiphytic bromeliad Guzmania monostachia as affected by drought and rewatering.

Juvenile plants of epiphytes such as bromeliads are highly prone to dehydration under drought conditions. It is likely that young epiphytes evolved mostly metabolic strategies to resist drought, which may include the plastic modulation of the enzymatic antioxidant system and crassulacean acid metabolism (CAM). Few studies have investigated such strategies in juvenile epiphytes, although such research is important to understand how these plants might face drought intensification derived from potential climatic alterations.

Potentiation of antibiotic activity of aminoglycosides by natural products from Cordia verbenacea DC.

Medicinal plants are often the only therapeutic resource for many communities and ethnic groups. Cordia verbenacea DC., "Erva-baleeira," is one of the species of plants currently used to produce a phytotherapeutic product extracted from its leaves.