Publications by authors named "Victoria Atanasova"
Objective: Early diagnosis of nosocomial infections in newborns is a great challenge, because in the initial phase of systemic infection, clinical symptoms are often non-specific, and routinely used hematological markers are not sufficiently informative. The aim of this study was to determine the potential of early inflammatory markers to diagnose late-onset neonatal sepsis-procalcitonin (PCT), interleukin 6 (IL-6), interleukin 8 (IL-8) and endocan (ESM-1).
Material And Methods: A prospective clinical-epidemiological study was conducted in a third-level NICU in Pleven, Bulgaria.
Safety of Re-dosing Nirsevimab Prior to RSV Season 2 in Children With Heart or Lung Disease.
J Pediatric Infect Dis Soc
August 2023
Article Synopsis
- A study on children with congenital heart disease or chronic lung disease found that 200 mg nirsevimab is as safe as palivizumab for RSV prevention.
- Nirsevimab showed effective serum levels that could help protect healthy infants from severe RSV disease.
- The results suggest that nirsevimab could also be effective for children at high risk of severe RSV during their second RSV season.
Efficacy of nirsevimab against respiratory syncytial virus lower respiratory tract infections in preterm and term infants, and pharmacokinetic extrapolation to infants with congenital heart disease and chronic lung disease: a pooled analysis of randomised controlled trials.
Lancet Child Adolesc Health
March 2023
Article Synopsis
- Nirsevimab is a monoclonal antibody shown to protect healthy infants from RSV-related lower respiratory tract infections in two clinical trials (phase 2b and MELODY), demonstrating safety similar to the existing drug palivizumab!* -
- Infants were dosed based on weight (50 mg for those <5 kg and 100 mg for ≥5 kg) and both the pooled efficacy and safety of nirsevimab were analyzed, particularly in infants at higher risk for severe RSV infections due to health conditions or preterm birth.* -
- The primary goal was to determine the incidence of RSV LRTI requiring medical attention within 150 days post-injection, with secondary focuses on hospital admissions and very
Background: Experiences afforded by natural settings promote health by helping people to build new adaptive capacities and to restore existing capacities. The aim of this study was to examine relations among restorative experience, mindfulness, rumination and psychological resilience in pathways linking residential greenspace to anxiety and depression symptoms.
Methods: We sampled 529 university students residing in Plovdiv, Bulgaria.
The aim of this study was to assess the thyroid status of pregnant women on the basis of biochemical indicators and to evaluate the potential risk of developing iodine deficiency as a result of tobacco smoke exposure by assessing the association between urinary thiocyanate levels and the manifestation of iodine deficiency. The study included 219 pregnant women from the town of Plovdiv and Plovdiv District in Southern Bulgaria. The levels of urinary iodine, thyroid-stimulating hormone (TSH), free thyroxine (FT4), and urinary thiocyanate as indicators of tobacco smoke exposure were measured.
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