Publications by authors named "Victoria Alexander"

Invasive meningococcal disease (IMD) is a severe illness that can have devastating effects; outbreaks are uncommon in the United States. Vaccination is the preferred control measure for IMD outbreaks when a defined population at risk (e.g.

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  • Some cells without nerves (aneural cells) might think in strange or irrational ways, like making wrong guesses.
  • This paper looks at how these cells can learn and adapt by making surprising connections, similar to creative thinking.
  • Three examples show how this kind of learning happens: immune cells attacking their own body, pea plants reacting to wind as if it's light, and a medicine that confuses the body about what is itself and what is not.
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  • The study systematically reviewed clinical articles on necrotising otitis externa (NOE) to enhance best practices in diagnosis and management, registering on PROSPERO and adhering to PRISMA guidelines.
  • A total of 70 articles involving 2,274 patients were analyzed, revealing that most studies were retrospective case series with variable case definitions, the majority being older males with a high prevalence of diabetes.
  • The review highlighted the need for better quality research due to inconsistencies in diagnosis and treatment practices, emphasizing the urgency for a standardized case definition and minimum reporting requirements for future studies.
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As COVID-19 vaccines moved from the controlled environment of clinical trials to use in real-world settings, it has been important to evaluate vaccine effectiveness. A retrospective cohort study was designed to identify cases of SARS-CoV-2 infection that occurred between January 17-June 30, 2021 in fully vaccinated Virginia residents. Of the fully vaccinated population of Virginia at the end of the study period (N = 4,271,505), 2445 (0.

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A 63-year-old male presented with a prolonged history of bilateral ear discharge, otalgia, and hearing loss. The patient required a significant number of investigations prior to obtaining a diagnosis. Subsequent investigations identified keratoacanthoma affecting the external ear canal (EAC).

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  • EUS-guided needle-based confocal laser endomicroscopy (EUS-nCLE) can help identify high-grade dysplasia/adenocarcinoma (HGD-Ca) in intraductal papillary mucinous neoplasms (IPMNs), but traditionally requires manual analysis.
  • Researchers developed two computer-aided diagnosis (CAD) algorithms using convolutional neural networks (CNNs) to automate and improve the accuracy of IPMN diagnosis and risk assessment.
  • The study showed that these CNN-CAD algorithms outperformed established guidelines in sensitivity and accuracy for detecting HGD-Ca, indicating their potential for real-time clinical application with future enhancements.
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  • * Thirteen patients underwent ICG-FA during their procedures, and the results led to changes in the surgical approach in 31% of the cases due to better identification of tissue perfusion issues.
  • * The findings suggest that ICG-FA can accurately pinpoint risks of poor tissue healing, indicating its potential as a beneficial tool in complex surgical operations involving rectal and vaginal reconstruction.
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For Bourdieu, the field of cultural production is comprised of an autonomous and a heteronomous sector. A heteronomous sector is one that is interpenetrated by the commercial field. I discuss an arena that, until recently, was part of the relatively autonomous sector in the field of cultural production - the supported arts sector in the United Kingdom - and argue that it became more heteronomous, due to the penetration by the state.

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Salivary bypass tubes (SBT) are increasingly used to prevent pharyngocutaneous fistula (PCF) following laryngectomy and pharyngolaryngectomy. There is minimal evidence as to their efficacy and literature is limited. The aim of the study was to determine if SBT prevent PCF.

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Objective: Head and neck teratomas are rare and malignant change is rarer still. This is a report detailing all of the teratomas treated by the ear, nose and throat or craniofacial teams over the last 28 years at our institution. Examining the common presenting and radiological features as well as our success rates compared to the current literature.

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Objectives: Ganglioneuroblastomas represent a histological subgroup of the rare neuroblastic tumours with intermediate malignant potential arising from neural crest progenitor cells of sympathetic nerves. Diagnosis can often be difficult based on imaging alone. We describe 4 cases of children presenting with a solitary neck mass with histology ultimately revealing ganglioneuroblastoma.

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A 10-year-old boy on an insulin pump with frequent episodes of hypoglycaemia, admitted to administering insulin to cover sweet intake using the pump prime function, thereby bypassing the bolus history that his mother monitored. This case demonstrates children's resourcefulness and technical abilities, and the difficulties parents experience in providing appropriate support.

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Recognition memory requires judgments of the previous occurrence of stimuli made on the basis of the relative familiarity of individual objects, or by integrating information concerning objects and location, or by using recency information. The present study examined the role of the medial prefrontal cortex (mPFC) and perirhinal cortex (PRH) in these distinct recognition memory processes using a series of behavioral tests: a novel object preference task, an object-in-place task, and a temporal order memory task. Also, a disconnection procedure was used to test whether these regions form components of an integrated system for recognition memory.

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