Publications by authors named "Victoria A Cuello"

Article Synopsis
  • The study investigates the behavior of Piezo1 channels, which open in response to mechanical pressure, focusing on their transition from closed to open states.
  • Researchers used advanced pressure-clamp recordings to analyze new subconductance states of Piezo1, revealing that pressure increases the open state while reducing closed states.
  • By employing Markov-chain modeling, the team developed a four-state kinetic model that accurately describes the channel's function, aiding future research into Piezo1's role in different cell types.
View Article and Find Full Text PDF