Publications by authors named "Victori Fiol"
Front Cell Dev Biol
March 2023
Article Synopsis
- LMNA-related muscular dystrophy can lead to serious heart issues, including dilated cardiomyopathy (DCM) and harmful arrhythmias, affecting pediatric patients diagnosed with conditions like Emery-Dreifuss muscular dystrophy and limb-girdle muscular dystrophy.
- A study monitored 28 pediatric patients, revealing that 20% experienced dangerous arrhythmias, with some requiring implantable defibrillators, and identified early-onset EDMD patients as having the worst heart outcomes.
- The findings indicate a need for specific heart care guidelines for children with these conditions to prevent sudden death, especially as early neurologic symptoms may be linked to worse cardiac prognosis.
