Wound Healing Properties and Antimicrobial Effects of Keay Fruit Husk Extract in a Rat Excisional Wound Model.

Background: Keay (Family: Fabaceae) () fruit husk is commonly used in northern Ghana for wound treatment. However, this folk claim remains to be confirmed scientifically.

Objective: This study investigated wound healing and antimicrobial effects of fruit husk extract (PCFHE) by using excision wound model in rats.

Alkaloidal Extract Improves CCl-Induced Hepatocellular Carcinoma-Like Phenotypes in Rats.

Background: Despite the enrollment of new small molecules such as Sorafenib for the treatment of hepatocellular carcinoma (HCC), HCC still remains a significant contributor to cancer-related mortality and morbidity globally. is long suspected of possessing anticancer bioactive compounds that may hold the prospect of adjunctive therapy against inflammation-related cancers such as HCC.

Objective: This study assessed the effects of an alkaloidal extract of the leaves of on CCl/olive oil (1 : 1 v/v)-induced HCC-like phenotypes in rats.

Leaf Extract Reverses Alloxan/Nicotinamide-Induced Diabetes Mellitus in Rats through Hormonal (Insulin, GLP-1, and Glucagon) and Enzymatic (-Amylase/-Glucosidase) Modulation.

Background: is used in folk medicine across Afro-Asian regions of the world. Earlier, glucose lowering and pancreato-protective effects of leaf extract (APLE) was confirmed experimentally in STZ/nicotinamide-induced diabetic rats; however, the underlying mechanism of antidiabetic effect and pancreato-protection remained unknown.

Objective: This study elucidated antidiabetic mechanisms and pancreato-protective effects of APLE in diabetic rats.