Ileal pouch anal anastomosis: analysis of outcome and quality of life in 3707 patients.

Background: Ileal pouch anal anastomosis (IPAA) is the treatment of choice for chronic, medically refractory mucosal ulcerative colitis, indeterminate colitis, familial adenomatous polyposis (FAP), and a select group of patients with Crohn's disease.

Aim: : We report outcomes, complications, and quality of life (QOL) in a cohort of 3707 patients treated at our institution from January 1984 to March 2010.

Methods: Data were collected from a prospectively maintained database and chart review of 3707 consecutive primary IPAA cases.