Background: This review seeks to investigate the clinically relevant bone graft materials in single-level transforaminal lumbar interbody fusion (TLIF) procedures as defined by (1) primary outcomes (ie, fusion rates and complication rates) and (2) patient-reported outcomes (ie, visual analog scale [VAS] and Oswestry disability index [ODI]). Because of the advantages in stimulating bone growth, autologous bone grafts such as the iliac crest bone graft (ICBG) have been the gold standard. Numerous alternatives to ICBG have been introduced.
View Article and Find Full Text PDFBackground Context: Anterior cervical discectomy and fusion (ACDF) and cervical disc arthroplasty (CDA) are established surgical options for the treatment of cervical radiculopathy, myelopathy, and cervical degenerative disc disease. However, current literature does not demonstrate a clear superiority between ACDF and CDA.
Purpose: To investigate procedural and patient-reported outcomes of ACDF and CDA among patients included in the Michigan Spine Surgery Improvement Collaborative (MSSIC) database.
We present avidity sequencing, a sequencing chemistry that separately optimizes the processes of stepping along a DNA template and that of identifying each nucleotide within the template. Nucleotide identification uses multivalent nucleotide ligands on dye-labeled cores to form polymerase-polymer-nucleotide complexes bound to clonal copies of DNA targets. These polymer-nucleotide substrates, termed avidites, decrease the required concentration of reporting nucleotides from micromolar to nanomolar and yield negligible dissociation rates.
View Article and Find Full Text PDFBackground: The effect of preoperative symptom duration (PSD) on patient-reported outcomes (PROs) in anterior cervical discectomy and fusion (ACDF) for radiculopathy is unclear.
Objective: To determine whether PSD is a predictor for PRO after ACDF for radiculopathy.
Methods: The Michigan Spine Surgery Improvement Collaborative registry was queried between March, 2014, and July, 2019, for patients who underwent ACDF without myelopathy and PROs (baseline, 90 days, 1 year, 2 years).
Background Context: The indications for surgical intervention of axial back pain without leg pain for degenerative lumbar disorders have been limited in the literature, as most study designs allow some degree of leg symptoms in the inclusion criteria.
Purpose: To determine the outcome of surgery (decompression only vs. fusion) for pure axial back pain without leg pain.
The introduction of heavy metal-free biomass into the sewage sludge (SS) pyrolysis can effectively improve the biochar properties and reduce the bioavailability and toxicity of heavy metals (HMs) in blended biochar. Herein, this study aimed to understand the biochar properties and associated environmental risks of HMs, by comparing the residual contents from the co-pyrolysis of SS with various organic fractions of municipal solid waste (OFMSW) at 550 °C and pyrolysis alone at different temperatures between 350 and 750 °C. The results indicated that, compared with SS pyrolysis alone, co-pyrolysis of SS with various OFMSW (except PVC) lead to lower biochar yields but with higher pH values (increased between 21.
View Article and Find Full Text PDFStudy Design: Cadaveric study.
Objective: To evaluate accuracy, radiation exposure, and surgical time of a new robotic-assisted navigation (RAN) platform compared with freehand techniques in conventional open and percutaneous procedures.
Methods: Ten board-certified surgeons inserted 16 pedicle screws at T10-L5 (n = 40 per technique) in 10 human cadaveric torsos.
Leaching kinetics of trace metals from incineration bottom ashes (IBA) under diffusion and advection were investigated through leaching tests of compacted granulars of IBAs and their packed columns with seawater eluent for 64 days and 26 days, respectively. Metal fluxes were distinct among species while linearily decreased at log-log scales as a function of time. Short-term environmental risks for Cu, Ni and Pb were identified under advection.
View Article and Find Full Text PDFIncineration bottom ash (IBA) faces challenges for its sustainable recycling due to the absence of scenario-specific risk assessment. Environmental risk assessment was carried out via a case study incorporating key factors to dominate human exposures during IBA utilization in land reclamation. Three research components echoing respective IBA leaching, exposures, and consequences were performed under a supportive framework to elaborate these interlinked key factors and unveil the potential environmental risks.
View Article and Find Full Text PDFInfants and children under 6 years old spend most of daily time in Child Care Centers (CCCs), especially in the tropical regions like Singapore. Environmental exposure and associated risk during this early critical developmental stage is of great public concern. In this study, seven representative volatile organic compounds (VOCs) and five typical phthalates were analyzed in the indoor and outdoor air samples collected from 32 Singapore CCCs.
View Article and Find Full Text PDFData from large-scale field trial experiments simulating the application of incineration bottom ash (IBA) for land reclamation were re-explored, to understand the spot-specific leaching characteristics and re-adsorption of heavy metals associated with various reclamation scenarios. Data showed that IBA leaching changed significantly as a function of seawater depth rather than time. The application of a chute had a minor effect on the total metal leached amounts; however, it would magnify the gradient of leaching concentrations across depths.
View Article and Find Full Text PDFThe microbial safety of swimming pool waters (SPWs) becomes increasingly important with the popularity of swimming activities. Disinfection aiming at killing microbes in SPWs produces disinfection by-products (DBPs), which has attracted considerable public attentions due to their high frequency of occurrence, considerable concentrations and potent toxicity. We reviewed the latest research progress within the last four decades on the regulation, formation, exposure, and treatment of DBPs in the context of SPWs.
View Article and Find Full Text PDFBackground: Most studies have evaluated 30-d readmissions after lumbar fusion surgery. Evaluation of the 90-d period, however, allows a more comprehensive assessment of factors associated with readmission.
Objective: To assess the reasons and risk factors for 90-d readmissions after lumbar fusion surgery.
Recycling of incineration bottom ashes (IBA) is attracting great interest as it is considered as a vital aspect for closing the waste loop to achieve sustainable development at the growing cities around the world. Various laboratory-testing methods are developed to assess the release potential of heavy metals - one of the most important concerns of using IBA, by reflecting the release conditions of heavy metals from IBA based on the targeted land reclamation application scenarios and corresponding environmental conditions. However, realistic release of the concerned elements in actual application with the presence of complex environment could possibly deviate from the outcomes produced by leaching tests carried out in the laboratory.
View Article and Find Full Text PDFBottom ashes generated from municipal solid waste incineration have gained increasing popularity as alternative construction materials, however, they contains elevated heavy metals posing a challenge for its free usage. Different leaching methods are developed to quantify leaching potential of incineration bottom ashes meanwhile guide its environmentally friendly application. Yet, there are diverse IBA applications while the in situ environment is always complicated, challenging its legislation.
View Article and Find Full Text PDFIntroduction: Biological particles deposit on air handling system filters as they process air. This study reports and interprets abundance and diversity information regarding biomass accumulation on ordinarily used filters acquired from several locations in a university environment.
Methods: DNA-based analysis was applied both to quantify (via DNA fluorometry and qPCR) and to characterize (via high-throughput sequencing) the microbial material on filters, which mainly processed recirculated indoor air.
Recent studies report high concentrations of haloacetic acids (HAAs), a prevalent class of toxic disinfection by-products, in swimming pool water (SPW). We investigated the removal of 9 HAAs by four commercial reverse osmosis (RO) and nanofiltration (NF) membranes. Under typical SPW conditions (pH 7.
View Article and Find Full Text PDFWe investigated the removal of haloacetic acids (HAAs) from swimming pool waters (SPWs) by two nanofiltration membranes NF270 and NF90. The strong matrix effect (particularly by Ca) on membrane rejection prompts us to systematically investigate the mechanistic role of Ca in HAA rejection. At typical SPW pH of 7.
View Article and Find Full Text PDFEnviron Monit Assess
January 2017
One-dimensional boring presents limitations on mapping the refuse profile in old landfills owning to waste heterogeneity. Electrical imaging (EI) and multiple-analysis of surface wave (MASW) were hereby deployed at an old dumping ground in Singapore to explore the subsurface in relation to geotechnical analysis. MASW estimated the refuse boundary with a higher precision as compared to EI, due to its endurance for moisture variation.
View Article and Find Full Text PDFThe ever-increasing consumption of various cytostatic drugs (CSDs) has attracted growing public concern in recent years. The photodegradation of 8 CSDs was investigated using a low-pressure UV-254Hg lamp, resulting in fluence-based first-order kinetic rate constants in the range of (0.20-6.
View Article and Find Full Text PDFSodium hypochlorite (NaClO) is the most commonly used disinfectant in pool treatment system. Outdoor pools usually suffer from the strong sunlight irradiation which degrades the free chlorine rapidly. In addition, more pools start to adopt the recirculation of swimming pool water, which intensifies the disinfection by-product (DBP) accumulation issue.
View Article and Find Full Text PDFEnviron Sci Pollut Res Int
September 2016
We conducted multiday continuous monitoring of indoor and outdoor particulate matter (PM) in classrooms with fan-assisted natural ventilation (NV) at five primary schools in Singapore. We monitored size-resolved number concentration of PM with diameter 0.3-10 μm at all schools and alveolar deposited surface area concentrations of PM with diameter 0.
View Article and Find Full Text PDFThe purpose of this study was to track the long-term trends of contaminants distribution in the old landfill of Singapore through monitored natural attenuation and to explore the main parameters that rule such transition. Contaminants distribution, including dissolved organic matter (DOM), inorganic species, heavy metals, and organic compounds, was investigated via monitoring wells in the years 1997, 2004 and 2011. The data revealed that the distribution of contaminants possessed selective attention of spots associated with leachate movement.
View Article and Find Full Text PDFHeavy metals and some metalloids are the most significant inorganic contaminants specified in toxicity characteristic leaching procedure (TCLP) in determining the safety of landfills or further utilization. As a consequence, a great deal of efforts had been made on the development of miniaturized analytical devices, such as Microchip Electrophoresis (ME) and μTAS for on-site testing of heavy metals and metalloids to prevent spreading of those pollutants or decrease the reutilization period of waste materials such as incineration bottom ash. However, the bottleneck lied in the long and tedious conventional TCLP that requires 18 h of leaching.
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