Publications by authors named "Victor T Milev"
JAACAP Open
December 2023
Article Synopsis
- The study aims to systematically review differences in white matter microstructure between adolescents with and without depressive disorders, focusing on the neural mechanisms of depression.
- A total of 14 studies were included, analyzing 1,510 adolescents and revealing significant differences in regions such as the uncinate fasciculus and corpus callosum, with most studies finding decreased fractional anisotropy in those with depression.
- The findings highlight potential microstructural abnormalities in specific brain circuits associated with depression, but caution is advised due to small sample sizes and possible reporting biases in the studies reviewed.
