Sinus bradycardia associated with daclizumab in liver transplant recipients: report of 3 cases.

Daclizumab is a commonly used immunosuppressive agent for prophylaxis of solid organ rejection. Although rare, the cardiovascular adverse effects of daclizumab include sinus tachycardia, hypotension, and hypertension. Here, we report 3 patients who developed significant and prolonged sinus bradycardia after receiving daclizumab following orthotopic liver transplant.

Effect of lower limb compression devices on thermodilution cardiac output measurement.

Objective: The aim of this study was to determine whether lower limb (calf) sequential compression devices (SCDs) have a significant effect on thermodilution cardiac output measurements using a pulmonary artery catheter.

Design: Prospective clinical investigation.

Setting: Surgical and neurosurgical intensive care units in a university hospital.