Publications by authors named "Victor M Lopes Dos Santos"
Clin Colorectal Cancer
September 2022
Article Synopsis
- The ICAR trial investigated the safety and effectiveness of chemotherapy (IC) followed by chemoradiation (CRT) with or without aspirin (ASA) in patients with high-risk locally advanced rectal cancer.
- Results showed that while the treatment was generally safe and well-tolerated, adding ASA did not improve MRI tumor response, leading to the trial's closure.
- Key outcomes included a 30.4% clinical complete response rate after treatment and promising 2-year disease-free survival (DFS) and 3-year overall survival (OS) rates, at 83.1% and 81.5%, respectively.
