Publications by authors named "Victor M Chua"
The venom of cone snails has been proven to be a rich source of bioactive peptides that target a variety of ion channels and receptors. α-Conotoxins (αCtx) interact with nicotinic acetylcholine receptors (nAChRs) and are powerful tools for investigating the structure and function of the various nAChR subtypes. By studying how conotoxins interact with nAChRs, we can improve our understanding of these receptors, leading to new insights into neurological diseases associated with nAChRs.
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- * The study characterizes a specific peptide from Drilliidae venom, named cdg14a, which is small and rich in disulfide bonds, and shows effects on mouse behavior, causing increased excitability in certain nerve cells.
- * Findings indicate that cdg14a could influence specific potassium channels, highlighting the potential of Drilliidae venoms as a source for developing new therapeutic agents targeting ion channels in the nervous system.