Publications by authors named "Victor Landa-Jaime"

The venoms of Conus snails contain neuroactive peptides named conotoxins (CTXs). Some CTXs are nicotinic acetylcholine receptor (nAChRs) antagonists. nAChRs modulate the release of neurotransmitters and are implicated in several pathophysiologies.

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The biodiversity of mollusks, particularly cephalopods, has not been exhaustively determined in the Revillagigedos ecoregion, which is a biodiversity hotspot for several marine groups located in the Tropical East Pacific Province. In our study, we detected and examined ocellate octopuses from Socorro and Clarion Islands, and determined their identity using morphological criteria and molecular data from two mitochondrial genes (COIII and COI). The taxon identified was , a species considered endemic to the Galapagos Archipelago.

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Article Synopsis
  • Snails produce venoms with peptides like α-conotoxins that block nicotinic acetylcholine receptors (nAChRs), which are important for nerve signal transmission.
  • Researchers isolated and tested 38 fractions from the venom extract, finding that fractions F7 and F16 significantly inhibited responses from human α7 nAChRs.
  • The active peptide from fraction F7 was identified and named αD-PiXXA; it inhibits ACh-induced responses in a specific way, affecting only certain receptor types.
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The first case of partial albinism registered in the Mexican Pacific by the blue lobster is presented. The specimen was collected on the southern coast of Jalisco know as Punta "El Estrecho". It constitutes one of the few registered cases of albinism in invertebrates from the Eastern Tropical Pacific.

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Article Synopsis
  • - Conus marine snails, found mainly in tropical areas, have about 500 species that use specialized venoms composed of peptides (called conotoxins) to catch prey and defend against threats.
  • - Conotoxins target specific proteins in the nervous system, such as ion channels and receptors, making them valuable for research and drug development due to their high specificity and affinity.
  • - The study focused on analyzing cDNAs encoding conotoxin precursors in three vermivorous Conus species from the Mexican Pacific, resulting in the identification of 30 distinct precursors with diverse predicted toxins targeting various nicotinic acetylcholine receptor types.
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