Publications by authors named "Victor G M Chel"

Background: Observational studies have reported an inverse association between ultraviolet (UV) radiation and hypertension. The aim of this study was to assess differences in blood pressure changes between persons with dementia receiving UV light versus vitamin D (VD) supplementation.

Methods: Post-hoc analysis of randomized controlled trial data concerning nursing home residents with dementia (N = 61; 41 women, mean age 84.

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There are indications that ultraviolet B (UVB) exposure has beneficial effects on well-being through mechanisms other than vitamin D synthesis alone. We conducted a randomized controlled multicenter trial to compare the effects of UVB light and vitamin D supplementation (VD) in terms of the well-being of nursing home residents with dementia. Participants were randomly assigned to the intervention group (UVB group, = 41; half-body UVB irradiation, twice weekly over 6 months, with 1 standard erythema dose (SED)) or to the control group (VD group, = 37; 5600 International units (IU) cholecalciferol supplementation once a week).

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Background: Human and animal studies have shown that exposure to ultraviolet light can incite a chain of endocrine, immunologic, and neurohumoral reactions that might affect mood. This review focuses on the evidence from clinical trials and observational studies on the effect of ultraviolet light on mood, depressive disorders, and well-being.

Methods: A search was made in PubMed, Embase, Web of Science, Cochrane, Psychinfo, CINAHL, Academic Search Premier and Science Direct, and the references of key papers, for clinical trials and observational studies describing the effect of ultraviolet light applied to skin or eyes on mood, depressive disorders, and well-being.

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Article Synopsis
  • The study aimed to explore the relationship between vitamin D supplementation and testosterone levels in men, given previous mixed findings on the topic.
  • Three independent trials were conducted involving male patients with heart failure, nursing home residents, and non-Western immigrants, where participants received either vitamin D or a placebo.
  • While vitamin D levels increased significantly in participants who received the supplementation, there was no corresponding increase in testosterone levels across all studies, indicating no causal link.
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