Inborn errors of immunity are known to influence susceptibility to mycobacterial infections. The aim of this study was to characterize the genetic profile of nine patients with mycobacterial infections (eight with BCGitis and one with disseminated tuberculosis) from the Republic of Moldova using whole-exome sequencing. In total, 12 variants in eight genes known to be associated with Mendelian Susceptibility to Mycobacterial Disease (MSMD) were detected in six out of nine patients examined.
View Article and Find Full Text PDFGlobally, 21 percent of young women are married before their 18th birthday. Despite some progress in addressing child marriage, it remains a widespread practice, in particular in South Asia. While household predictors of child marriage have been studied extensively in the literature, the evidence base on macro-economic factors contributing to child marriage and models that predict where child marriage cases are most likely to occur remains limited.
View Article and Find Full Text PDFThere is scarce empirical evidence on the relation between migration and child health in Moldova and Georgia-two post-Soviet countries with large out-migration flows in the region. This study uses nationally representative data collected in 2011-2012 in Moldova ( = 1601) and Georgia ( = 1193) to investigate how children's health associates with five transnational characteristics: migrant and return-migrant household types, parental migration and parental divorce, maternal and/or paternal migration and caregiver's identity, the duration of migration, and remittances. Findings show that, regardless of the transnational family setting, children of migrants have overall positive or no differing health compared to children in non-migrant households.
View Article and Find Full Text PDFThis study empirically measures the perceptions towards maternal and paternal migration of male and female children who stay behind in Ghana. It analyses survey data collected in 2010 among secondary school children aged 11-18 in four urban areas with high out-migration rates: the greater Accra region, Kumasi, Sunyani and Cape Coast ( = 1965). The results show significant gendered differences in how children perceive parental migration.
View Article and Find Full Text PDFThis study is the first to employ panel data to examine well-being outcomes-self-rated health, happiness, life satisfaction, and school enjoyment-of children in transnational families in an African context. It analyzes data collected in 2013, 2014, and 2015 from secondary schoolchildren and youth (ages 12-21) in Ghana (N = 741). Results indicate that children with fathers, mothers, or both parents away and those cared for by a parent, a family, or a nonfamily member are equally or more likely to have higher levels of well-being as children in nonmigrant families.
View Article and Find Full Text PDFWhen parents migrate, leaving their children in the origin country, transnational families are formed. Transnational family studies on children who are "left behind" indicate that children suffer psychologically from parental migration. Many of the factors identified as affecting children's responses to parental migration however are not considered in child psychology and family sociology studies.
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