Publications by authors named "Victor Cano"
Article Synopsis
- Endometrial cancer is influenced by estrogens and the study investigates the impact of environmental pollutants, specifically xenoestrogens, on this type of cancer.
- The research involved analyzing serum samples from 156 patients with endometrial cancer and 150 control subjects to measure the combined estrogenic activity related to these pollutants.
- Results showed no significant difference in xenoestrogen levels between cases and controls, but indicated a complex relationship between exposure levels and cancer risk, with some associations identified for intermediate exposure categories.
Article Synopsis
- Endometrial cancer is the most common gynecological cancer in developed countries, and its incidence is expected to rise, prompting the need to identify modifiable risk factors for prevention.
- This study investigates the link between occupational pesticide exposure and endometrial cancer using data from 174 cancer cases and 216 control subjects in Spain, utilizing structured questionnaires and a job-exposure matrix to assess pesticide exposure.
- The findings indicate a significant association between pesticide exposure and endometrial cancer, particularly for insecticides, fungicides, and herbicides, with the strongest links found in agricultural activities, suggesting a need for further exploration of pesticides’ role in cancer development.
Article Synopsis
- The study investigated the increasing prevalence of endometrial cancer and aimed to improve molecular classification and detection using non-invasive cervicovaginal samples.
- It included 139 patients with endometrial cancer and 107 controls, analyzing a total of 339 samples through next-generation sequencing (NGS) to identify genetic mutations.
- Results showed that 73% of cancer cases had detectable mutations, with varying prognoses based on specific mutations, highlighting the potential of using non-invasive methods for better diagnosis and treatment.
Article Synopsis
- Screenwide is a case-control study conducted in Spain from 2017 to 2021 that looked at women with endometrial and ovarian cancers, along with BRCA1/2 and MMR pathogenic variant carriers, to identify risk factors and molecular biomarkers for these cancers.
- Participants provided detailed personal and medical information, along with biological samples like blood and self-collected vaginal specimens, to facilitate comprehensive analyses.
- Preliminary findings from a pilot study indicate that certain genetic variants associated with tumors can be effectively detected in less invasive samples, suggesting potential for improved early detection strategies for gynecological cancers.
Background: Circadian disruption caused by night work has been associated with hormonal-related cancers such as breast and prostate cancer. Data on the role of circadian factors in the aetiology of endometrial cancer, an oestrogen-associated cancer, are scarce.
Methods: We examined the association between endometrial cancer and night shift work, chronotype (a characteristic correlating with preference for morning or evening activity) and sleep duration, in 180 incident cases and 218 hospital controls.
Giant cell ependymoma (GCE) is a very uncommon variant of ependymoma, known for having varying degrees of nuclear pleomorphism. There are only 34 reported cases of GCE in the English literature. We describe an additional case of a young woman who presented with a tumor located in sacral soft tissue, which was not connected to the spinal cord and did not show additional lesions in the central nervous system.
View Article and Find Full Text PDFMicrobial status of apical root canal system of human mandibular first molars with primary apical periodontitis after "one-visit" endodontic treatment.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod
February 2005
Objective: To assess the in vivo intracanal microbial status of apical root canal system of mesial roots of human mandibular first molars with primary apical periodontitis immediately after one-visit endodontic treatment. The residual intracanal infection was confirmed by correlative light and transmission electron microscopy.
Study Design: Sixteen diseased mesial roots of mandibular first molars were treated endodontically, each in one visit.