Publications by authors named "Victor Augusto Camarinha de Castro Lima"
Genetic description of VanD phenotype vanA genotype in vancomycin-resistant Enterococcus faecium isolates from a Bone Marrow Transplantation Unit.
Ana Paula Marchi Lauro Vieira Perdigão Neto Marina Farrel Côrtes Victor Augusto Camarinha de Castro Lima Roberta Cristina Ruedas Martins
Braz J Microbiol
March 2022
Article Synopsis
- Vancomycin-resistant Enterococcus faecium (VREfm) poses significant risks for hospital infections, with specific resistance patterns linked to the vanA and vanD genes that require further exploration.
- The study found that VRE isolates with a VanD-vanA phenotype showed a mix of susceptibility to teicoplanin and high resistance to vancomycin, while not sharing a common genetic lineage among samples.
- Key genetic features revealed variations in important resistance genes and insertion elements, indicating the complexity of genetic mechanisms at play, emphasizing the need for deeper research into these patterns.
Phenotypic and genotypic characteristics of a carbapenem-resistant Serratia marcescens cohort and outbreak: describing an opportunistic pathogen.
Gladys Prado Elisa Teixeira Mendes Roberta Cristina Ruedas Martins Lauro Vieira Perdigão-Neto Maristela Pinheiro Freire Victor Augusto Camarinha de Castro Lima
Int J Antimicrob Agents
January 2022
Article Synopsis
- * A retrospective study reviewed cases of colonization and infection, analyzing 42 isolates, including environmental samples, for carbapenemase genes and genetic mutations, revealing key resistance mechanisms and virulence factors.
- * The findings suggested that a history of polymyxin use significantly increased the risk for infection and indicated that cross-transmission might be a factor in the spread of these resistant strains, emphasizing the importance of monitoring and controlling this pathogen.
Article Synopsis
- Yellow fever is a serious viral disease that can lead to liver damage, but this study focused on understanding the long-term effects of severe YF on liver health in survivors, specifically looking for liver fibrosis.* -
- Researchers evaluated 18 patients who survived a recent outbreak in Brazil using ultrasound technology to assess liver stiffness, with findings indicating a low occurrence of significant liver fibrosis among them.* -
- Age and cardiac failure appeared to be linked to increased liver stiffness, suggesting that certain risk factors could predict liver health post-YF, while a subset of patients treated with sofosbuvir showed no signs of liver fibrosis.*
To evaluate 30-day mortality in human immunodeficiency virus (HIV) and non-HIV patients who acquired a healthcare-associated infection (HAI) while in an intensive care unit (ICU), and to describe the epidemiological and microbiological features of HAI in a population with HIV.This was a retrospective cohort study that evaluated patients who acquired HAI during their stay in an Infectious Diseases ICU from July 2013 to December 2017 at a teaching hospital in Brazil.Data were obtained from hospital infection control committee reports and medical records.
View Article and Find Full Text PDFColistin-resistant Klebsiella pneumoniae co-harboring KPC and MCR-1 in a Hematopoietic Stem Cell Transplantation Unit.
Hermes Ryoiti Higashino Ana Paula Marchi Roberta Cristina Ruedas Martins Marjorie Vieira Batista Lauro Vieira Perdigão Neto Victor Augusto Camarinha de Castro Lima
Bone Marrow Transplant
July 2019
Article Synopsis
- Emergency medicine requires quick decision-making, but there's limited info about the profiles of emergency physicians in Brazil, particularly in Salvador.
- A study was conducted with interviews from 659 doctors in emergency departments of 25 hospitals, revealing they were mostly young (median age 34), with a significant proportion having received minimal emergency training.
- The findings show that only 13% of physicians were fully satisfied with their jobs, and a striking 81.3% plan to leave emergency medicine within 15 years, primarily due to high stress levels.
Colistin-resistant Enterobacteriaceae infections: clinical and molecular characterization and analysis of in vitro synergy.
Claudia M D de Maio Carrillho Juliana J Gaudereto Roberta Cristina Ruedas Martins Victor Augusto Camarinha de Castro Lima Larissa M de Oliveira
Diagn Microbiol Infect Dis
March 2017
Article Synopsis
- * Resistance was linked to chromosome mutations, and treatment varied, with 8 patients on monotherapy and 19 on combination therapy; the overall mortality rate was 37%.
- * In vitro tests showed a 74% synergy rate for combination therapies using colistin, amikacin, and tigecycline, but no significant survival difference was found based on drug combinations; major risk factors for mortality included dialysis and shock.