Publications by authors named "Vicky Wai Lai Chang"
Lancet Respir Med
April 2020
Article Synopsis
- Treatment of multidrug-resistant tuberculosis involves long-term use of second-line drugs, which can cause serious side effects like deafness and even death.
- A meta-analysis was conducted using individual patient data from studies on adverse events that required stopping anti-tuberculosis treatment, focusing on data from 2009-2016 and additional information from a WHO request in 2018.
- Findings revealed that certain drugs, such as levofloxacin and moxifloxacin, had low rates of adverse events resulting in treatment discontinuation, while second-line injectable drugs like amikacin showed higher rates of severe side effects.
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