The latex allergen hev B 5 is an antigen with repetitive murine B-cell epitopes.

Background: Hev b 5 is a potent latex allergen. In this study, we characterize the linear B-cell epitopes for three monoclonal antibodies (mAbs) to Hev b 5.

Methods: The mAbs included 2 IgG1 (6A10, 3G3) and 1 IgG2b (6F6) isotypes.

Lipid transfer protein from Hevea brasiliensis (Hev b 12), a cross-reactive latex protein.

Background: Latex-allergic individuals experience clinical cross-reactivity to a large number of fruits and vegetables. Much of the cross-reactivity can be attributed to Hev b 6, but evidence indicates that additional cross-reactive allergens may be present. A common pan-allergen, which has not previously been identified in latex, but may contribute to this cross-reactivity is lipid transfer protein (LTP).