Publications by authors named "Vickram V Anand"
Article Synopsis
- The meta-analysis examines how sex affects mortality risk in patients with acute coronary syndrome (ACS) who lack standard modifiable risk factors (referred to as SMuRF-less) compared to those who have at least one risk factor (SMuRF).
- It analyzed data from eight studies, revealing that women in the SMuRF-less group had higher in-hospital mortality rates than men, while men showed no significant increase in mortality.
- The findings indicate that women without cardiovascular risk factors face greater short- and medium-term mortality risks after an ACS event compared to their male counterparts.
Article Synopsis
- This study investigates how metabolic dysfunction-associated steatotic liver disease (MASLD) affects long-term survival in patients who have suffered an acute myocardial infarction (AMI) across different body weight categories.
- The four patient groups analyzed were obesity MASLD, non-obesity MASLD, obesity non-MASLD, and non-obesity non-MASLD, with findings showing that non-obesity MASLD had the highest risk of heart failure and long-term mortality.
- The results indicate that both obesity and non-obesity MASLD are significant predictors of all-cause mortality post-AMI, particularly highlighting the greater risk associated with non-obesity MASLD.
Article Synopsis
- The study aims to project cardiovascular disease (CVD) mortality trends and risk factors from 2025 to 2050 to aid healthcare planning.
- Using historical data and Poisson regression, projections indicate a significant increase in CVD prevalence (90%), crude mortality (73.4%), and DALYs (54.7%), with ischaemic heart disease and high blood pressure as major contributors.
- Despite a stable age-standardized CVD prevalence, the study underscores a concerning rise in crude mortality due to an aging population, prompting the need for effective healthcare strategies.
The burden of cardiovascular disease in Asia from 2025 to 2050: a forecast analysis for East Asia, South Asia, South-East Asia, Central Asia, and high-income Asia Pacific regions.
Lancet Reg Health West Pac
August 2024
Article Synopsis
- A study forecasts a 91.2% increase in crude cardiovascular disease (CVD) mortality in Asia from 2025 to 2050, despite a 23.0% decrease in the age-standardized mortality rate.
- Ischaemic heart disease and stroke will remain the top causes of mortality, with Central Asia experiencing the highest mortality rates while high systolic blood pressure is identified as the leading risk factor across most of Asia.
- The research highlights the need for targeted health interventions due to the significant variations in CVD burden across different regions in Asia.
Article Synopsis
- Malnutrition is linked to worse outcomes for patients with acute coronary syndrome (ACS), impacting their prognosis and survival rates.
- The study reviewed various nutritional assessment tools and analyzed data from 30 studies with over 37,000 patients, revealing that about one-third were malnourished, leading to a mortality rate of 20.59% among them.
- Results showed that malnutrition significantly increased the risk of all-cause mortality, regardless of ACS type, ethnicity, or income, highlighting the importance of addressing nutritional status in these patients.
Purpose Of Review: The objective of this manuscript is to examine the current literature on the epidemiology of metabolic dysfunction-associated steatotic liver disease (MASLD), its correlation with cardiovascular disease (CVD) outcomes, as well as to evaluate the update in nomenclature from non-alcoholic liver disease (NAFLD).
Recent Findings: The update of diagnostic criteria from NAFLD to MASLD reduces the stigma associated with alcohol consumption and poor health choices. It also shines a light on the crucial role of cardiometabolic risk factors in disease pathophysiology.
Article Synopsis
- - Recent research indicates that tirzepatide, a medication that interacts with gut hormones, effectively promotes weight loss in individuals with overweight or obesity, as shown in a systematic review and meta-analysis of clinical trials.
- - The analysis involved approximately 5800 patients, revealing that a significant percentage achieved notable weight loss (≥5%: 78.22%, ≥10%: 55.60%, ≥15%: 32.28%) and that higher doses of tirzepatide led to greater weight loss compared to placebo and another drug, semaglutide.
- - While there were some gastrointestinal side effects linked to tirzepatide, they were not substantially different from those experienced with semaglutide,
Article Synopsis
- Health literacy and illness perception significantly impact the management of cardiometabolic diseases, with this study examining the differences in attitudes and knowledge between individuals with and without metabolic risk factors (MFs).
- A survey of 345 participants revealed that those with MFs tended to have lower knowledge scores but higher perceived risks regarding cardiometabolic diseases like hypertension and diabetes.
- Despite their heightened awareness of risks, individuals with MFs showed only slight increases in taking preventive actions, highlighting a critical need to bridge the gap between knowledge and actual health behaviors.
Background: Low socioeconomic status (SES) is an important prognosticator amongst patients with acute coronary syndrome (ACS). This paper analysed the effects of SES on ACS outcomes.
Methods: Medline and Embase were searched for articles reporting outcomes of ACS patients stratified by SES using a multidimensional index, comprising at least 2 of the following components: Income, Education and Employment.
Article Synopsis
- Malnutrition and obesity are interconnected issues that affect global health, and trends in disability-adjusted life years (DALYs) and deaths related to both were analyzed using data from 204 countries from 2000 to 2019, with projections up to 2030.
- In 2019, malnutrition-related DALYs were higher in Africa and low SDI countries, while obesity-related DALYs increased annually, especially in the Eastern Mediterranean and middle SDI regions.
- The study predicts that while malnutrition-related DALYs may decrease, the burden of obesity will continue to rise significantly in the coming years, indicating a growing health crisis.
Objective: With rising prevalence of hypertension and obesity, the effect of hypertension in obesity remains an important global issue. The prognosis of the US general population with obesity based on hypertension control was examined.
Methods: This study examined participants from the National Health and Nutrition Examination Survey between 1999 and 2018.
Objective: The obesity epidemic is a global health concern with Asian countries facing one of the most rapid rises in obesity rates. However, given the underwhelming long-term efficacy of weight loss strategies, especially in Asia, this review aimed to explore barriers and facilitators to weight management of patients with overweight and obesity in Asia.
Methods: Medline, CINAHL, PsycINFO, and Web of Science were searched for articles discussing barriers and facilitators of treatment to obesity from the perspectives of both health care professionals (HCPs) and patients.