Lifestyle factors and the risk of a second breast cancer after ductal carcinoma in situ.

Background: Little information exists on lifestyle factors that affect prognosis after treatment for ductal carcinoma in situ (DCIS) breast cancer. Improved understanding of the role of lifestyle factors is important to survivors wishing to reduce their risk of a second breast cancer diagnosis.

Methods: We examined the association between body mass index (BMI), physical activity, and alcohol intake, and risk of a second breast cancer diagnosis among 1,925 DCIS survivors in the Wisconsin In Situ Cohort.

Fatty acid consumption and the risk of osteoporotic fracture.

Osteoporosis is a disease characterized by low bone mass and the structural deterioration of bone tissue. It is estimated that 44 million Americans and 55% of those over 50 years of age are currently affected by this disease. Among other risk factors for osteoporotic fracture, dietary fat in general and essential fatty acids (EFA) in particular have recently been investigated because of their suspected impact on the bone remodeling process.

Disease-free survival by treatment after a DCIS diagnosis in a population-based cohort study.

Randomized trials have demonstrated the efficacy of radiation and tamoxifen in reducing risk of second events after breast-conserving surgery (BCS) for ductal carcinoma in situ (DCIS), but the comparative effectiveness of mastectomy, BCS, and adjuvant treatments have not been established in community practice. We examined disease-free survival (DFS) among 1,676 DCIS cases diagnosed during 1995-2006 in the population-based Wisconsin In Situ Cohort study. Information on patient and tumor characteristics, treatments, and second breast cancer events were collected via a comprehensive review of data from patient interviews, the statewide cancer registry, and pathology reports.

Components of metabolic syndrome and risk of breast cancer by prognostic features in the study of osteoporotic fractures cohort.

Purpose: Metabolic syndrome (MetS) and most of its components have been previously associated with increased breast cancer risk. We hypothesized that increasing number of MetS components would be positively associated with breast cancer risk.

Methods: Data were obtained from the Study of Osteoporotic Fractures, a prospective cohort of women aged ≥65 enrolled between 1986 and 1988 and still being followed prospectively (n = 8,956).

Practical nurses' health and safety in nursing homes.

Purpose: Practical nurses (PNs) rated their general and emotional health and their employers' attention to their health and safety. These components were examined in relationship to work setting and intention to leave for the purpose of exploring workforce issues involving these important care providers of frail elders.

Design/methods: A relicensure survey mailed to all PNs in one rural state included the Minimum Data Set for nurse workforce supply plus questions from the Health and Retirement Survey.