Publications by authors named "Vichan Lorvidhaya"
Introduction: This study aimed to compare the cost utility of concurrent chemoradiation (CCRT) to CCRT followed by adjuvant chemotherapy (CCRT/ACT) in locally advanced cervical cancer (LACC) using provider and societal viewpoints.
Methods: Data from our trial which was a multi-centre study evaluating the efficacy of ACT compared to CCRT/ACT were entered into a decision tree model. The data included clinical probability, direct medical and non-medical costs, and utility obtained from the patients.
A randomized controlled trial comparing concurrent chemoradiation versus concurrent chemoradiation followed by adjuvant chemotherapy in locally advanced cervical cancer patients: ACTLACC trial.
Siriwan Tangjitgamol Ekkasit Tharavichitkul Chokaew Tovanabutra Kanisa Rongsriyam Tussawan Asakij Vichan Lorvidhaya
J Gynecol Oncol
July 2019
Article Synopsis
- The study aimed to evaluate the effectiveness of adding adjuvant chemotherapy (ACT) after standard concurrent chemoradiation therapy (CCRT) in patients with locally advanced cervical cancer.
- No significant difference in response rates or survival outcomes was observed between patients who received only CCRT and those who also received ACT, although systemic recurrences were lower in the ACT group.
- The findings suggest that adding ACT does not enhance overall treatment effectiveness compared to CCRT alone, despite some benefits in reducing systemic recurrences.