Publications by authors named "Vicente Simo"

Article Synopsis
  • Colon cancer is becoming more common in younger people, and treatment usually involves surgery and chemotherapy; however, neoadjuvant chemotherapy is being tested for its potential to improve survival rates.
  • This study is a randomized clinical trial that will compare two treatment groups: one receiving neoadjuvant chemotherapy, surgery, and adjuvant chemotherapy, and the other getting surgery followed by adjuvant chemotherapy.
  • The main goal is to see if neoadjuvant chemotherapy leads to better survival outcomes within two years, while also looking at other factors like tumor response and side effects.
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Article Synopsis
  • The study aimed to compare the effectiveness of transanal versus laparoscopic Total Mesorectal Excision in enabling sphincter-saving interventions for obese rectal cancer patients.
  • Out of 93 patients, the transanal group showed a significantly higher rate of sphincter-saving surgeries (97%) compared to the laparoscopic group (71%).
  • While both approaches had similar major complication rates, the transanal approach had no conversions to open surgery, suggesting it may offer safer outcomes in complex cases.
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We present the case of a 63-year-old male with long-term anal pain. A pelvic MRI was performed showing a tumor arising from the intersphincteric extending into the submucosal layer of the posterior rectal wall. The image was compatible with a cT4N0 ano-rectal carcinoma without any distant metastasis on the CT scan.

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Aim: The aim was to describe the range of possibilities and our group's clinical outcomes when performing different types of anastomosis during transanal total mesorectal excision (taTME).

Method: A retrospective analysis was performed based on four taTME series from 2016 to 2021. Inclusion criteria were patients with rectal cancer in whom a sphincter-saving low anterior resection by taTME was performed.

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Objective: the aim of the study was to analyze the management of colorectal cancer (CRC) patients diagnosed with CRC or undergoing elective surgery during the period of the SARS-CoV-2 pandemic.

Material And Methods: a multicenter ambispective analysis was performed in nine centers in Spain during a four-month period. Data were collected from every patient, including changes in treatments, referrals or delays in surgeries, changes in surgical approaches, postoperative outcomes and perioperative SARS-CoV-2 status.

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Background: Colorectal cancer is the third most frequent tumor in males and the second in females worldwide. In Spain, it is an important and growing health problem, and epidemiologic research focused on potential risk factors, such as environmental exposures, is necessary.

Objectives: To analyze the association between colorectal cancer risk and residential proximity to industries, according to pollution discharge route, industrial groups, categories of carcinogens and other toxic substances, and specific pollutants released, in the context of a population-based multicase-control study of incident cancer carried out in Spain (MCC-Spain).

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Background: There is no consensus regarding the gold standard technique for rectal cancer as Total Mesorectal Excision (TME) may be safely performed either by open or minimally invasive surgery. The laparoscopic approach, however, may carry technical difficulties. For this reason, a novel technique has emerged in the last decade combining a dual laparoscopic dissection (abdominal and transanal) to perform the TME technique (TaTME).

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Introduction: The aim of this study is to describe and evaluate our clinical short-term surgical results of laparoscopic transanal total mesorectal excision.

Methods: Analysis of 100 consecutive patients with mid and lower rectal cancer who underwent transanal total mesorectal excision from November 2013 to September 2018. Main outcomes described are operative data, morbidities, mortality and quality of the specimen.

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