Publications by authors named "Vicente Benites-Zapata"

Background: Molecular tests have contributed to reducing the mortality rate through early and accurate diagnosis of tuberculosis (TB). This is due to their low processing complexity and diagnostic accuracy superior to conventional methods.

Objective: To evaluate the diagnostic performance of Cobas MTB and Logix Smart MTB compared to Xpert MTB/RIF Ultra for pulmonary tuberculosis (PTB) and extrapulmonary tuberculosis (EPTB).

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  • * A meta-analysis of 28 studies, with a total of 29,195 participants, revealed an overall prevalence of 30.3%, with variation based on altitude levels.
  • * Key findings show that women had a higher prevalence (35.5%) than men (26.8%), and the disease components like abdominal obesity and low HDL cholesterol were notably common, while high blood pressure and high triglycerides were less frequent.
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Background: Some studies have reported that homocysteine, vitamin B12, and folic acid levels are associated with polycystic ovary syndrome (PCOS), whereas other studies yielded controversial results.

Objectives: This study aimed to systematize the available evidence of homocysteine, vitamin B12, and folate levels in women with and without PCOS.

Design: Systematic review and meta-analysis.

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  • This study reviews existing research on asprosin levels in patients with type 2 diabetes (T2D), metabolic syndrome (MetS), and obesity to explore its potential as a treatment for metabolic-endocrine disorders.
  • A systematic analysis of 26 studies found that individuals with T2D, MetS, and obesity had significantly higher asprosin levels compared to those without these conditions.
  • The results suggest that asprosin could serve as a biomarker for metabolic disorders, as its levels are notably elevated in T2D, MetS, and obesity patients.
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Aim: To determine the association between atherogenic markers, such as total cholesterol/high density lipoprotein cholesterol ratio (TC/HDL-C), triglycerides/HDL-C ratio (TG/HDL-C), and triglycerides-glucose index (TyG), and the risk of 1-year amputation in adults with diabetic foot in a tertiary level hospital.

Methods: Retrospective cohort study conducted in 162 adult patients with diabetic foot. The outcome was amputation, defined as "primary amputation in patients' clinical history after their first hospitalization due to foot ulcer.

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Background: Dengue has emerged as an unprecedented epidemic in Peru, and it is anticipated that this issue will escalate further owing to climate change. This study aimed to determine the risk factors associated with death from dengue in patients treated at Hospital II in Pucallpa, Peru.

Methodology: This retrospective cohort study collected information from the medical records of patients with a diagnosis of dengue treated at Hospital II Pucallpa-Peru between January 2019 and March 2023.

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  • * A systematic literature review analyzed 1359 articles, identifying 33 valid studies involving 96,909 animals, finding a pooled prevalence of 5.0% in birds, 1.0% in pigs, and 0.0% in cats and dogs.
  • * Although H5N1 appears less common in animals compared to other influenza strains, its potential to cause severe illness in humans underscores the importance of monitoring its prevalence and understanding contributing factors for effective prevention.
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  • A systematic review and meta-analysis was conducted to evaluate the effectiveness and safety of ivermectin in treating early COVID-19 in non-hospitalized patients, using data from five databases up to October 2023.
  • The analysis included 12 randomized controlled trials with over 7,000 adult patients, comparing ivermectin to standard care, placebo, or other active drugs, focusing on outcomes like hospitalization, mortality, adverse events, and clinical improvement.
  • The findings indicated that ivermectin did not significantly reduce hospitalization, mortality, or adverse events compared to control groups, leading to the conclusion that it should not be recommended for treating non-hospitalized COVID-19 patients.
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Introduction: Dengue is a vector-borne disease, especially important in tropical and subtropical areas. The first presentation of many arboviral diseases occurred mainly in animals, including multiple and , such as dengue.

Objective: To determine the serological and molecular frequency of the dengue virus in animals.

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  • Mpox, a zoonotic disease that became widespread in 2022, lacks comprehensive reviews on its occurrence in animals, prompting a systematic review and meta-analysis to determine its prevalence.
  • The study evaluated 15 reports and revealed a pooled prevalence of 16.0% in non-human primates, 8.0% in rodents, and 1.0% in shrews based on molecular or serological tests conducted on 2,680 animals.
  • The research highlights the need for further studies in various animal species to understand Mpox's natural infection rates and stresses the importance of a OneHealth approach for effective public health strategies.
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Objective: We aimed to review the available evidence on the association between vitamin B12, folate, and homocysteine levels with worse outcomes among COVID-19 patients.

Methods: The search was carried out in ten databases simultaneously run on 10 May 2023, without language restrictions. We included cross-sectional, case-control, and cohort studies.

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Objective: To assess the association between ethnicity and self-reported refractive errors (REs) among Peruvian children aged 7-11 years.

Materials And Methods: We conducted a cross-sectional study incorporating a secondary data analysis of 2017-2021 data from the Peruvian Demographic and Health Survey (DHS). REs and ethnicity were obtained from focal child's mother's report.

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Background And Aims: The presence of fungal infections has been described in patients after recovering from COVID-19. This study aims to conduct a systematic review of studies that reported fungal infections ( spp., , or spp.

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Objective: To synthesize the primary evidence on the efficacy and safety of visnadine on symptoms of sexual dysfunction (SD) in heterosexual women.

Methods: We conducted a systematic review of randomized clinical trials (RCTs) with a primary search without language restriction in PubMed/Medline, Scopus, Embase, Web of Science, Cochrane Library, and international clinical trial registries. Trials reporting the use of visnadine by any route in women with SD were eligible.

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Snakebites still constitute a significant public health problem in developing countries and are considered a neglected tropical condition by the WHO. Snake accidents are associated with substantial morbidity and mortality and may produce secondary complications, such as severe infections. The objective of this systematic review was to determine the prevalence of snakebite infections and characterize the bacteria isolated from these infections.

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We summarize the clinical trials (CTs) main characteristics, including members of ethnic minorities from Latin America. We carried out a systematic search in six databases. We made a descriptive synthesis of CTs, summarizing the characteristics, interventions, main findings, results, and conclusions reported.

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We aimed to determine the variations in the prevalence of childhood anemia according to the ethnic group before and during the COVID-19 pandemic in Peru. Secondary analysis of the Demographic and Family Health Survey during 2016-2021. The outcome variable was anemia, and the exposure variable was maternal ethnicity.

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Objective: To assess the relationship between the self-perceived consultation time and the knowledge of the proposed treatment.

Methods: Secondary data from a 2015 national survey of health services in Peru were analyzed. The self-perceived consultation time was calculated by asking how long it took from when you entered the consultation until you departed.

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Background: Human immunodeficiency virus (HIV) infection and sexually transmitted infections (STIs) are major global public health issues. Migrants represent a vulnerable group that faces multiple barriers to access to healthcare services, including HIV/STI testing. This study aimed to assess the factors associated with access to HIV/STI testing in male and female Venezuelan migrants in Peru.

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We aimed to conduct a scoping review to assess the profile of retracted health sciences articles authored by individuals affiliated with academic institutions in Latin America and the Caribbean (LAC). We systematically searched seven databases (PubMed, Scopus, Web of Science, Embase, Medline/Ovid, Scielo, and LILACS). We included articles published in peer-reviewed journals between 2003 and 2022 that had at least one author with an institutional affiliation in LAC.

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Aim: We performed a systematic review and meta-analysis to assess whether telomerase activity and telomere length are associated with breast cancer.

Methods: PubMed, Web of Science, Embase, LILACS, Scielo, Embase, and CNKI databases were searched to obtain relevant articles published through May 10, 2023, following PRISMA guidelines and a registered PROSPERO protocol (CRD42022335402). We included observational studies reporting telomerase activity or telomere length in patients with breast cancer compared with women with benign lesions or normal tissue (control women).

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Background: Despite improvements in health insurance coverage, out-of-pocket (OOP) health spending remains a public health issue in Peru, and OOP payment has implications for disease treatment in ethnic minorities. We aimed to analyze the ethnic disparities in the OOP payment and estimate the gaps related to observable risk factors in the OOP payment on medicines by ethnic conditions during 2014-2016 in Peru.

Study Design: cross-sectional study.

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Objective: To evaluate the factors associated with food insecurity (FI) among Venezuelan migrants residing in Peru. Secondarily, to evaluate the psychometric properties of the Food Insecurity Experience Scale (FIES).

Design: A cross-sectional study based on secondary data analysis of the 2022 Venezuelan Population Residing in Peru Survey (ENPOVE-2022, from the Spanish acronym) was conducted.

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Objective: To compare the mortality rates from COVID-19 among indigenous populations of the Amazon and Andean regions of Peru during the years 2020, 2021 and 2022.

Methods: Secondary analysis of 33,567 data from the COVID-19 Notification System of the National Epidemiology Center, Prevention and Control of Diseases (CDC-Peru), from the years 2020-2022. The variables were age, sex, belonging to the Andean or Amazonian ethnic group, number and type of symptoms and risk conditions, abnormal findings in chest X-rays, year of data collection for hospitalization and death from COVID-19.

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