Publications by authors named "Vibhu Banala"
Article Synopsis
- Affinity-based purification of adeno-associated virus (AAV) vectors is now favored over density-based methods for clinical applications, utilizing camelid single-domain antibodies that target AAV capsids.
- The study employed cryo-electron microscopy and 3D reconstruction to identify how these antibodies bind to various AAV serotypes, noting specific binding regions on the capsid.
- Findings reveal that certain amino acids on AAV capsids are crucial for ligand binding and can also neutralize viral infection, potentially aiding in the design of improved AAV vectors for purification processes.
Pain Relief after Surgical Decompression of the Distal Brachial Plexus.
J Brachial Plex Peripher Nerve Inj
January 2020
Brachial plexopathy causes pain and loss of function in the affected extremity. Entrapment of the brachial plexus terminal branches within the surrounding connective tissue, or medial brachial fascial compartment, may manifest in debilitating symptoms. Open fasciotomy and external neurolysis of the neurovascular bundle in the medial brachial fascial compartment were performed as a surgical treatment for pain and functional decline in the upper extremity.
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